Döl tutmayan (Repeat breeder) ineklerde PGF_{2\alpha} ve intrauterin köpük sprey (Rifaximina) uygulamalarının gebe kala oranı üzerine etkisinin araştırılması
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2001
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info:eu-repo/semantics/openAccess
Özet
Bu araştırmada ineklerde repeat breeder'a neden olan subklinik ve nonspesifık endometritisler, klinik ve mikrobiyolojik muayene yöntemi ile belirlenmeye çalışılarak tedavilerinde PGF_{2\alpha} ve intrauterin rifaximina uygulamalarının etkinliği araştırıldı. Çalışma materyalini, 3-9 yaşlı, en az 3 kez tohumlandığı halde gebe kalmayan ve düzenli östrüs siklusu gösteren fark.lı ırktan 36 baş inek oluşturdu. Klinik muayeneler sonucu genital organlarında makroskopik bir bozukluk belirlenemeyen ve repeat breeder olarak nitelenen hayvanların endometriumundan bakteriyolojik muayene amacıyla swab, histopatolojik muayene amacıyla da biyopsi örneği alındı. Hayvanlar mikrobiyolojik muayene sonucuna göre iki gruba ayrıldı. Buna göre bakteriyolojik muayene sonucu üreme olmayan 25 baş inek birinci grubu, üreme tespit edilen 11 baş inek ise ikinci grubu oluşturdu. Birinci grup hayvanlara 11 gün arayla kontrolsüz 2 kez 25 mg Dinoprost tromethamine (Dinolytic, Eczacıbaşı) im enjekte edildi. Son enjeksiyondan 72-96 saat sonra iki kez tohumlandı. İkinci gruptaki hayvanlara ise siklusun 10. gününde 25 mg Dinoprost tromethamine im verilerek, enjeksiyondan bir hafta sonra 100 mg rifaximina (Fatroximin intrauterin Foam, Fatro) intrauterin verildi. Hayvanlar bu uygulamadan sonra oluşan ilk östrüslerinde tohumlandılar.Her iki grupta da östrüsü geriye dönen hayvanlar ikinci kez tohumlandı. Mikrobiyolojik muayene sonucunda 36 baş inekten 11'inde (% 30.6) mikroorganizma izole edildi. Bu ineklerin 5'inde (% 41.7) \beta -haemolytic streptecoccus, 4'ünde (% 33.3) Staphylococcus ssp ve 3'ünde (% 25.0) Corynebacterium ssp tespit edildi. Histopatolojik muayene yapılan 36 baş ineğin biyopsi materyalinden 19'unda fark.lı derecelerde endometritis teşhis edilirken kalan 17 baş hayvanda herhangi bir patolojik lezyona rastlanmadı.Repeat breeder ineklere uygulanan fark.lı iki tedavi yöntemi sonrasında PGFia grubunda % 44.0, rifaximina grubunda ise % 63.6 gebelik oranı elde edildi. Repeat breeder hayvanların teşhis ve tedavisinde klinik muayene yöntemleri dışında mikrobiyolojik muayene yönteminin de önemli olduğu ve rifaximina köpük formülasyonun gerek endometriuma iyi yayılması ve gerekse rezistans olayının olmaması nedeniyle tedavide PGF_{2\alpha}'dan daha etkili olduğu belirlendi. Sonuç olarak, ineklerde subklinik ve nonspesifık endometritislere bağlı repeat breeder'ın tedavisinde PGF_{2\alpha} ve rifaximina uygulamalarının etkili olduğu kanısına varıldı.
ft this study the effect of intramuscular PGF_{2\alpha} and intrauterine rifaximina was determined following the clinical and microbiological diagnoses of subclinic and non specific endometritis resulting in dairy cattle. Total of 36 cows, aging between 3-9 years having normal estrous cycles with no pregnancy following at least 3 unsuccessful inseminations, were used. Biopsy specimens for histopathological examination and swab for bacteriological cultures were obtained from endometrium of repeat breeders showing no macroscopic evidence of any defectiveness of genital organs based on rectal palpation and anamneses. The cows were divided in to 2 subgroups according to microbiological results. Based on that, 25 cows with positive bacteriological results were assigned group I and 11 cows with negative bacteriological results were assigned group II. The cows in-group I received 25 mg Dinoprost tromethamine (Dinolytic, Eczacıbaşı) Intramuscularly twice 11 days apart. These cows, 72-96 hours after the last injections, were inseminated twice. The cows in-group II had 25 mg of Dinoprost tromethamine intramuscularly on the day 10 of estrous cycle. One week after this injection, 100 mg of rifaximina (Fatroximin Intrauterine Foam, Fatro) was given intrauterine.The cows were inseminated on the appearance of first estrous cycle. The cows with repeating estrous cycles were reinseminated. Eleven cows (30.6 %) out of 3,6 cows had positive bacteriological results. Five cows (41.7 %) had \beta -hemolytic streptococcus, 4 cows (33.3 %) had Staphylococcus ssp, 3 cows (25.0 %) had Corynebacterium ssp. while 19 cows had varying degrees of and endometritis, the other 17 cows didn't have any pathologic lesions. Forty-four percent and 63.6 % of pregnancy rates were obtained in group I and group II respectively through the PGF_{2\alpha} on the treatment of repeat breeders. Microbiological examination, along with clinical examination are important on the diagnoses and treatment of repeat breeders, having no resistance with well' dissipation to endometrium rifaximina foam formulation was found to be more effective than PGF_{2\alpha}. It was concluded that PGF_{2\alpha} and rifaximina applications on the treatment of repeat breeder, resulting from subclinic and nonspecific endometritis were effective.
ft this study the effect of intramuscular PGF_{2\alpha} and intrauterine rifaximina was determined following the clinical and microbiological diagnoses of subclinic and non specific endometritis resulting in dairy cattle. Total of 36 cows, aging between 3-9 years having normal estrous cycles with no pregnancy following at least 3 unsuccessful inseminations, were used. Biopsy specimens for histopathological examination and swab for bacteriological cultures were obtained from endometrium of repeat breeders showing no macroscopic evidence of any defectiveness of genital organs based on rectal palpation and anamneses. The cows were divided in to 2 subgroups according to microbiological results. Based on that, 25 cows with positive bacteriological results were assigned group I and 11 cows with negative bacteriological results were assigned group II. The cows in-group I received 25 mg Dinoprost tromethamine (Dinolytic, Eczacıbaşı) Intramuscularly twice 11 days apart. These cows, 72-96 hours after the last injections, were inseminated twice. The cows in-group II had 25 mg of Dinoprost tromethamine intramuscularly on the day 10 of estrous cycle. One week after this injection, 100 mg of rifaximina (Fatroximin Intrauterine Foam, Fatro) was given intrauterine.The cows were inseminated on the appearance of first estrous cycle. The cows with repeating estrous cycles were reinseminated. Eleven cows (30.6 %) out of 3,6 cows had positive bacteriological results. Five cows (41.7 %) had \beta -hemolytic streptococcus, 4 cows (33.3 %) had Staphylococcus ssp, 3 cows (25.0 %) had Corynebacterium ssp. while 19 cows had varying degrees of and endometritis, the other 17 cows didn't have any pathologic lesions. Forty-four percent and 63.6 % of pregnancy rates were obtained in group I and group II respectively through the PGF_{2\alpha} on the treatment of repeat breeders. Microbiological examination, along with clinical examination are important on the diagnoses and treatment of repeat breeders, having no resistance with well' dissipation to endometrium rifaximina foam formulation was found to be more effective than PGF_{2\alpha}. It was concluded that PGF_{2\alpha} and rifaximina applications on the treatment of repeat breeder, resulting from subclinic and nonspecific endometritis were effective.
Açıklama
Anahtar Kelimeler
Ziraat Mühendisliği
Kaynak
Hayvancılık Araştırma Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
11
Sayı
2
Künye
Aköz M., Dinç D. A. (2001). Döl tutmayan (Repeat breeder) ineklerde PGF_{2\alpha} ve intrauterin köpük sprey (Rifaximina) uygulamalarının gebe kala oranı üzerine etkisinin araştırılması. Hayvancılık Araştırma Dergisi, 11(2), 51-56.
