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Öğe Benign Rheumatoid Nodules – Reply(AMER MEDICAL ASSOC, 1994) Yavuz, Haluk; Özel, Ahmet; Erkul, İbrahimWe think that our article1 has been misunderstood. The word "swelling" was used to describe the nodule by parents. The patient had only nodules and limited motion of the arms in the morning. Pain orjoint swelling were not present either in the history or on physical examination. Morning stiffness alone cannot be regarded as a criterion of objective arthritis in the diagnosis of JRA.2 The negative test resultfor rheumatoidfactor does not exclude the diagnosis of benign rheumatoid nodules as well as JRA.3 We think that the criteriafulfilling the diagnosis of JRA have not developed in our patient.Öğe Corticosteroid-Therapy and Severe Chickenpox(MOSBY-ELSEVIER, 1994) Yavuz, Haluk; Özel, Ahmet; Erkul, İbrahimTo the Editor." We read with interest the article by Abzug and Cotton. 1 Although some reports indicate that varicella infections may have a more severe clinical course in patients receiving corticosteroids, there are studies suggesting the opposite. 2 A metaanalysis on the corticosteroid-infection association revealed that use of prednisone may increase the risk of infectious complications when the dose exceeds 10 mg daily or 700 mg cumulatively)Öğe Differences in Immunoglobulin Preparations and Outcome of Kawasaki Disease(MOSBY-ELSEVIER, 1996) Yavuz, Haluk; Özel, AhmetIt is known that morbidity and mortality rates for Kawasaki disease (KD) vary from one community to another. Cardiac involvement and sequelae were greater and mortality rates were higher in the British Isles than in Japan.Öğe Early onset of IgA nephropathy presenting with nephrotic syndrome(2008) Peru, Harun; Elmacı, Ahmet Midhat; Akın, Fatih; Orhan, Diclehan; Özel, Ahmet5 yasında erkek hasta hastanemize vucudunda sislik nedeniyle basvurdu. İdrar analizinde mikroskopik hematüri ve nefrotik düzeyde proteinüri saptandı. Kan basıncı normal sınırlardaydı. Kompleman 3 ve 4 düzeyleri normal, ANA negatifti. Hastaya 4 hafta süreyle prednizolon tedavisiverilmesine rağmen proteinürisi sebat ettiği için perkütan böbrek biyopsisi yapıldı. Biyopsi IgA nefropatisi ile uyumluydu. Tedaviye siklofosfamid eklendi. Proteinuri 12 haftalık siklofosfamid tedavisinden sonra düzeldi. Bu IgA nefropati olgusu erken yasta nefrotik sendrom kliniği ile ortaya çıkması sebebiyle rapor edilmistir.Öğe Early onset of IgA nephropathy presenting with nephrotic syndrome(2008) Peru, Harun; Elmacı, Ahmet Midyat; Akın, Fatih; Orhan, Diclehan; Özel, AhmetA 5-year-old boy was admitted to our hospital with the complaint of swelling of his whole body. Urine analysis revealed nephrotic range proteinuria and microscopic hematuria. He was normotensive. Complement C3 and C4 levels were normal. Antinuclear antibodies (ANA) were negative. A percutaneous renal biopsy was performed because of the persistent proteinuria despite a full course of 4 weeks of steroid treatment. The renal biopsy was consistent with IgA nephropathy. Then cyclophosphamide was added to the treatment. Proteinuria disappeared after 12 weeks of cyclophosphamide treatment. This case of IgA nephropathy is reported because of the early age of onset and because of presenting with nephrotic syndrome.Öğe Honey Poisoning in Turkey(LANCET LTD, 1991) Yavuz, Haluk; Özel, Ahmet; Akkuş, İdris; Erkul, İbrahimSIR,- Food poisoning associated with honey is not uncommon in the Black Sea region of Turkey. Nectar from some plants in the area is toxic. This form of poisoning is mentioned in Xenophon's Anabasis but published reports are very rare. We describe here a large series.Öğe Peripheral Gangrene Complicating Hemolytic Uremic Syndrome in a Child(Springer-Verlag, 2003) Özel, Ahmet; Çalışkan, Ümran; Gücer, ŞafakA patient with hemolytic uremic syndrome (HUS) developed peripheral gangrene involving all fingers and toes. There was no history of bloody diarrhea. Hypocomplementemia was present, with a serum C3 concentration of 41 mg/dl. Acute renal failure was treated with peritoneal dialysis for 4 months. He received daily fresh-frozen plasma infusions and plasmapheresis on alternate days for ten sessions, followed by once-weekly sessions. He was anuric for 9 weeks. All medial and distal phalanxes became necrotic and were removed surgically. The renal biopsy findings were consistent with HUS. This is the second report of peripheral gangrene during the course of HUS in childhood.Öğe Short-Term, High-Dose Corticosteroid-Therapy in Childhood Acute Immune Thrombocytopenic Purpura(Mosby-Elsevier, 1995) Yavuz, Haluk; Özel, Ahmet; Erkul, İbrahimWe read with interest the article by Blanchette et al. 1 A therapeutic regimen that increases the platelet count above a safe level for preventing intracranial hemorrhage by use of orally administered corticosteroids in relatively low doses would be the preferred form of therapy, but we think that the continuation of this therapy for 3 weeks is disadvantageous because of the development of untoward effects and the prolongation of therapy. Side effects may occur with the continued daily use of corticosteroids, and the hy pothalamus-pituitary-adrenal system would be suppressed if steroids were administered for periods longer than 15 days. 2 Moreover, effective treatment without any side effects have been reported in studies in which methylprednisolone was used in very high doses orally for 1 week. 3 We are still investigating'the effect of orally administered methylprednisolone, 10 mg/kg per day, for 5 days in the treatment of acute immune thrombocytopenic purpura in children. The preliminary data for 10 patients revealed mild elevation of the blood glucose concentration in two patients on day 3 and in the occult blood in the stool in one patient on day 7, which were transient. The mean platelet count increased from 21 X 109/L, to 47 × 109/L on the third day of therapy. The platelet count decreased below 20 x 109/L in only one patient during follow-up.
