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Öğe The first case of anal myiasis caused by chrysomya albiceps (wiedemann, 1819) in a dog infested with rhiphicephalus sanguineus (latreille, 1806) ticks suspected to cause paralysis in Turkey(KAFKAS UNIV, VETERINER FAKULTESI DERGISI, 2019) Ceylan, Onur; Dik, Bilal; Ilhan, Ceylan; Ider, Merve; Gulersoy, ErdemA four-year-old Kangal dog with hundreds of ixodid ticks in the head and neck regions and a large number of myiasis larvae in the anal region were brought to Selcuk University, Faculty of Veterinary Medicine, Department of Internal Medicine. A paralysis covering the anterior and posterior extremites, except the head region was determined in the dog. It was suspected that the paralysis was caused by ticks on the dog after elimination of some other disease. However, no definitive diagnosis was made for paralysis. Collected ticks were identified as Rhiphicephalus sanguineus (Latreille, 1806). The myiasis larvae collected from the anal region were identified as second and third instars of Chrysomya albiceps (Wiedemann, 1819). As a result, it is suggested that C. albiceps and Rh. sanguineus should be considered in the etiology of myiasis and tick paralysis cases, respectively.Öğe Intravenous pharmacokinetics of moxifloxacin following simultaneous administration with flunixin meglumine or diclofenac in sheep(WILEY, 2019) Altan, Feray; Corum, Orhan; Yildiz, Ramazan; Faki, Hatice Eser; Ider, Merve; Ok, Mahmut; Uney, KamilIn this study, the pharmacokinetics of moxifloxacin (5 mg/kg) was determined following a single intravenous administration of moxifloxacin alone and co-administration with diclofenac (2.5 mg/kg) or flunixin meglumine (2.2 mg/kg) in sheep. Six healthy Akkaraman sheep (2 +/- 0.3 years and 53.5 +/- 5 kg of body weight) were used. A longitudinal design with a 15-day washout period was used in three periods. In the first period, moxifloxacin was administered by an intravenous (IV) injection. In the second and third periods, moxifloxacin was co-administered with IV administration of diclofenac and flunixin meglumine, respectively. The plasma concentration of moxifloxacin was assayed by high-performance liquid chromatography. The pharmacokinetic parameters were calculated using a two-compartment open pharmacokinetic model. Following IV administration of moxifloxacin alone, the mean elimination half-life (t(1/2 beta)), total body clearance (Cl-T), volume of distribution at steady state (V-dss) and area under the curve (AUC) of moxifloxacin were 2.27 hr, 0.56 L h(-1) kg(-1), 1.66 L/kg and 8.91 hr*mu g/ml, respectively. While diclofenac and flunixin meglumine significantly increased the t(1/2 beta) and AUC of moxifloxacin, they significantly reduced the Cl-T and V-dss. These results suggest that anti-inflammatory drugs could increase the therapeutic efficacy of moxifloxacin by altering its pharmacokinetics.Öğe The Relationship Between Hemogram Parameters and Mortality in Neonatal Calves with Diarrhea(Selçuk Üniversitesi, 2023 Mart) Ider, Merve; Naseri, Amir; Erturk, AlperAmaç: Bu çalışmada, farklı etiyolojik etkenlere bağlı gelişen neonatal buzağı ishalinde hemogram parametrelerinin mortalite ile ilişkisinin ortaya konulması amaçlandı. Gereç ve Yöntem: Çalışmaya 50 ishalli buzağı dahil edildi. Buzağılar hayatta kalma durumlarına göre iyileşen ve ölen buzağılar olarak 2 gruba ayrıldı. Ayrıca dışkı hızlı test kitinde ishale neden olan etiyolojik etken temelinde bakteriyel (E. coli), viral (Rotavirüs ve Koronavirüs) ve paraziter (Cryptosporidium parvum) olmak üzere 3 alt gruba ayrıldı. Total lökosit (WBC), lenfosit (Lym), monosit (Mon), granülosit (Gra), eritrosit (RBC), ortalama eritrosit hacmi (MCV), hematokrit (HCT), ortalama eritrosit hemoglobini (MCH), ortalama eritrosit hemoglobin konsantrasyonu (MCHC), eritrosit dağılım genişliği (RDW), hemoglobin (Hb) ve trombosit (PLT) düzeyleri ölçüldü. Bulgular: Etiyolojiden bağımsız olarak, ölen buzağıların MCHC düzeyleri hayatta kalan buzağılardan daha düşüktü (cut-off: 32.15 g/dL, 68% sensitive, 62% spesifite, p = 0.041). Ayrıca, viral etiyolojiye sahip, ölen buzağıların MCHC düzeyleri, hayatta kalan buzağılardan daha düşüktü (cut-off: 31.75 g/dL, 85% sensitive, 75% spesifite, p = 0.029). E. coli etiyolojisine sahip ölen buzağıların RBC düzeyleri, hayatta kalan buzağılardan daha düşüktü (cut-off: 9.27 ×103 cells/mL, 83% sensitive, 84% spesifite, p = 0.024). C. parvum ile enfekte buzağıların hemogram parametrelerinde istatistiksel olarak anlamlı farklılık yoktu. Öneri: MCHC ve RBC düzeyleri, yenidoğan buzağı ishalinde mortalite tahmininde istatistiksel olarak anlamlıydı. Hemogram parametrelerinin diğer kan parametreleri (kan gazı vb.) ile birlikte değerlendirilmesi mortalite tahmininde daha faydalı olabilir.Öğe Sustained Polymorphic Ventricular Tachycardia in a Calf(Selçuk Üniversitesi, 2017 Haziran) Naseri, Amir; Ider, Merve; Ok, MahmutSürekli polimorfik ventriküler taşikardi, ventrikülerin birden fazla odağından kaynaklanan bir ventriküler aritmidir ve ventriküler fibrilasyon gibi ölümcül aritmilere ve ani ölüme yol açabilmektedir. Yedi günlük Holştayn dişi bir buzağı Selçuk üniversitesi, Veteriner Fakültesi, büyük hayvan hastanesine ani kollaps şikayeti ile getirildi. Elektrokardiyografi bulguları sürekli polimorfik ventriküler taşikardi’yi gösterdi. Kardiyak hasar şüphesi kardiyak troponin I (cTnI), kreatin kinaz- MB (CK-MB) ve kreatin fosfokinaz (CPK) düzeylerindeki artışla doğrulandı.Öğe Treatment of complete urethral obstruction by using pneumatic lithotripsy in a dog: A preliminary report(KAFKAS UNIV, VETERINER FAKULTESI DERGISI, 2016) Maden, Mehmet; Ider, Merve; Parlak, Kurtulus; Ozturk, AhmetIn this preliminary case presentation, use of the minimally invasive cystoscopic pneumatic lithotripsy technique in the treatment of complete urethral obstruction in a dog has been described. The animal of the case comprised a 5-year old Chihuahua presenting with difficulty during urination and inability to urinate for the previous 2 days. Post-renal azotemia and hematuria was determined. Urethral stones causing complete urethral obstruction were visualized via cystoscopy, fragmented with a pneumatic lithotripter and the stone fragments were removed using the voiding urohydropulsion method. In conclusion, the pneumatic lithotripsy method was successfully used in the treatment of complete urethral obstruction.
