Meibomian Gland Dysfunction and Tear Film Abnormalities in Rosacea

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dc.contributor.authorZengin, N.
dc.contributor.authorTol, H.
dc.contributor.authorGündüz, K.
dc.contributor.authorOkudan, S.
dc.contributor.authorBalevi, S.
dc.contributor.authorEndoğru, H
dc.date.accessioned2020-03-26T16:24:32Z
dc.date.available2020-03-26T16:24:32Z
dc.date.issued1995
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIn order to determine the relationship between meibomian gland dysfunction and tear film abnormalities in rosacea, tear film flow and stability and meibomian gland function were assessed in 43 consecutive patients. Schirmer, tear film break-up time, and meibomian gland function values in patients with ocular rosacea (n=28) were found to be significantly decreased as compared with those of the patients with only cutaneous involvement and control patients (p>0.05). In patients with dermatologic rosacea (n=15) these values were not different from those of the age- and sex-matched controls (p>0.05). The effects of tetracycline and meibomian gland expression therapy were also investigated in patients with ocular rosacea. Neither meibomian gland expression therapy nor tetracycline administration had beneficial effects on decreased tear secretion, but tetracycline improved the break-up time values. Our findings showed a positive relationship between tear film abnormalities and meibomian gland dysfunction in patients with rosacea. Decreased tear secretion in patients with ocular rosacea would seem to be a result of structural changes secondary to meibomian gland dysfunction, and short break-up time might be due to an abnormal meibum composition.en_US
dc.identifier.citationZengin, N., Tol, H., Gündüz, K., Okudan, S., Balevi, S., Endoğru, H, (1995). Meibomian Gland Dysfunction and Tear Film Abnormalities in Rosacea. Cornea, 14(2), 144-146.
dc.identifier.endpage146en_US
dc.identifier.issn0277-3740en_US
dc.identifier.issue2en_US
dc.identifier.pmid7743796en_US
dc.identifier.startpage144en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/16289
dc.identifier.volume14en_US
dc.identifier.wosWOS:A1995QH57500024en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorZengin, N.
dc.institutionauthorTol, H.
dc.institutionauthorGündüz, K.
dc.institutionauthorOkudan, S.
dc.institutionauthorBalevi, S.
dc.institutionauthorEndoğru, H
dc.language.isoenen_US
dc.publisherLIPPINCOTT-RAVEN PUBLen_US
dc.relation.ispartofCorneaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectRosaceaen_US
dc.subjectMeibomian Gland Dysfunctionen_US
dc.subjectShirmer I Testen_US
dc.subjectTear Break-up Timeen_US
dc.subjectTetracyclineen_US
dc.subjectMeibomian Gland Expressionen_US
dc.titleMeibomian Gland Dysfunction and Tear Film Abnormalities in Rosaceaen_US
dc.typeArticleen_US

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