Development and validation of a LC method for the analysis of phenolic acids in Turkish salvia species

Basit Öğe Kaydı
dc.contributor.authorKan, Y.
dc.contributor.authorGoekbulut, A.
dc.contributor.authorKartal, M.
dc.contributor.authorKonuklugil, B.
dc.contributor.authorYilmaz, G.
dc.date.accessioned2020-03-26T17:17:13Z
dc.date.available2020-03-26T17:17:13Z
dc.date.issued2007
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAn accurate, simple, reproducible, and sensitive method for determination of rosmarinic, caffeic, cklorogenic, and gallic acids in 12 Salvio species growing naturally in Anatolia, has been developed and validated. The phenolic acids were separated using a mu Bondapack C-18 column by gradient elution with a flow rate of 1.0 mL min(-1), which was adjusted to deliver firstly o-phosphoric acid 0.085% in water, 0.085% in methanol, and 0.085% in 2-propanol (80:10: 10, v/v/v), then decreased gradually (60:20:20, v/v/v) during 20 min with a flow rate of 1.0 mL min(-1). The samples were monitored at 220 nm for gallic acid and 330 nm for rosmarinic, caffeic, and chlorogenic acids using pkoto-diode array detection. The linear range of detection for gallic, chlorogenic, caffeic, and rosmarinic acids were between 0.051-101.4, 0.207-103.6, 0.100-100, and 0.201-100.5 mu g mL(-1), respectively. The linearity, range, peak purity, selectivity, system performance parameters, precision, accuracy, and robustness had also acceptable values. The developed method was applied to the flower, leaf, stem, and root parts of the Salvia species.en_US
dc.identifier.doi10.1365/s10337-007-0278-7en_US
dc.identifier.endpageS152en_US
dc.identifier.issn0009-5893en_US
dc.identifier.issn1612-1112en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpageS147en_US
dc.identifier.urihttps://dx.doi.org/10.1365/s10337-007-0278-7
dc.identifier.urihttps://hdl.handle.net/20.500.12395/21314
dc.identifier.volume66en_US
dc.identifier.wosWOS:000250331100024en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSPRINGER HEIDELBERGen_US
dc.relation.ispartofCHROMATOGRAPHIAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectcolumn liquid chromatographyen_US
dc.subjectphenolic acidsen_US
dc.subjectrosmarinic and caffeic acidsen_US
dc.subjectsalviaen_US
dc.titleDevelopment and validation of a LC method for the analysis of phenolic acids in Turkish salvia speciesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu