Light microscopic evaluation of the nucleolar organiser regions of skin cells of the dogs subjected to therapeutic ultrasounds

dc.contributor.authorOgurtan, Zeki
dc.contributor.authorAydin, Mehmet Faruk
dc.contributor.authorCeylan, Cengiz
dc.contributor.authorCelik, Ilhami
dc.date.accessioned2020-03-26T17:27:10Z
dc.date.available2020-03-26T17:27:10Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractA possible use of some argyrophilic nucleolar organiser region (AgNOR) parameters as a biological counter to predict the biological behaviour of basal epidermal cells and dermal fibroblasts in dogs subjected to therapeutic ultrasound (US) exposure was determined. All the dogs, except the control dogs, had US treatment at an intensity of 0.5 W/cm(2) (SATA), frequency of 1.0 MHz, pulsed 2 ms on and 8 ms off for 5 min daily for 10 d. Full thickness skin samples were taken on days 4, 18, 32, 46, and 74 following cessation of 10 d US application and right after the 10(th) d of US exposure. A statistically significant difference immediately at the end of day 10 of US exposure was found for all parameters measured, except NOR diameters of the stratum basale cells. All the measured parameters, except NOR numbers of fibroblasts in the dermis, returned to normal (control) values by day 74 indicating that the therapeutic effect of US at the given characteristics lasts at least longer than 46 d regarding thickness of the stratum corneum, longer than 32 d regarding NOR numbers in the cells of the stratum basale, and NOR diameters in the cells of the stratum basale, and longer than 74 d regarding NOR numbers in fibroblasts. The results presented herein suggest that there is a correlation between the longevity of ultrasound effect and the alteration of AgNORs parameters and their characteristics. Considering the longer duration of reversible alterations in our study, it would be reasonable to determine the effectiveness of ultrasound by AgNOR counting.en_US
dc.identifier.endpage470en_US
dc.identifier.issn0042-4870en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage467en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22491
dc.identifier.volume52en_US
dc.identifier.wosWOS:000259713100032en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherNATL VETERINARY RESEARCH INSTen_US
dc.relation.ispartofBULLETIN OF THE VETERINARY INSTITUTE IN PULAWYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectdogen_US
dc.subjectskinen_US
dc.subjectultrasounden_US
dc.subjectAgNOR proteinsen_US
dc.titleLight microscopic evaluation of the nucleolar organiser regions of skin cells of the dogs subjected to therapeutic ultrasoundsen_US
dc.typeArticleen_US

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