A study on in vitro enzyme inhibitory properties of Asphodeline anatolica: New sources of natural inhibitors for public health problems

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dc.contributor.authorZengin, Gökhan
dc.date.accessioned2020-03-26T19:22:59Z
dc.date.available2020-03-26T19:22:59Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAsphodeline species are traditionally used as food and medicines. The different extracts (acetone, methanol and water) from different parts (stem, root, seed and leaf) of Asphodeline anatolica were screened for inhibitory potentials on cholinesterase, tyrosinase, alpha-amylase and alpha-glucosidase. Enzyme inhibitory effects were investigated by using microplate reader. All studied extracts exhibited remarkable inhibitory effects on the tested enzymes. Generally, acetone and methanol extracts have higher potentials than water extracts. Also, the enzyme inhibitory activities of the extracts varied significantly according to the plant parts as well as the solvent used. R-Met (7.42 mgGALAEs/g extract) and St-Ac (10.74 mgGALAEs/g extract) had the highest acetylcholinesterase and butrylcholinesterase inhibitory activity, respectively. R-Met (22.48 mgKAEs/g extract) exhibited the strongest tyrosinase inhibitory effects, while Se-Ac had the most potent activity on both alpha-amylase (2.53 mmolACAEs/g extract) and alpha-glucosidase (6.70 mmolACAEs/g extract). The results suggested that the A. anatolica extract may be useful for food and medicinal applications. (c) 2015 Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.indcrop.2015.12.033en_US
dc.identifier.endpage43en_US
dc.identifier.issn0926-6690en_US
dc.identifier.issn1872-633Xen_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage39en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.indcrop.2015.12.033
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33214
dc.identifier.volume83en_US
dc.identifier.wosWOS:000370894000006en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE BVen_US
dc.relation.ispartofINDUSTRIAL CROPS AND PRODUCTSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAsphodelineen_US
dc.subjectCholinesteraseen_US
dc.subjectTyrosinaseen_US
dc.subjectGlucosidaseen_US
dc.subjectPharmaceuticalen_US
dc.subjectTurkeyen_US
dc.titleA study on in vitro enzyme inhibitory properties of Asphodeline anatolica: New sources of natural inhibitors for public health problemsen_US
dc.typeArticleen_US

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