Determining the Effect of Sufentanil on Propofol Injection Pain

dc.contributor.authorSaritas, Tuba Berra
dc.contributor.authorBorazan, Hale
dc.contributor.authorKara, Inci
dc.contributor.authorTuncer, Sema
dc.contributor.authorOtelcioglu, Seref
dc.date.accessioned2020-03-26T18:24:48Z
dc.date.available2020-03-26T18:24:48Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectives: Propofol is a general anesthetic. Its most important disadvantage is pain on injection. Our aim was to evaluate the effectiveness of sufentanil on propofol injection pain (PIP). Design: Case control randomized double-blind study Setting: Anesthesia department of Selcuk University Meram Medical School, Turkey Subjects: A total of 160 adults, 18 to 65 years, ASA I-II patients, scheduled for operations under general anesthesia, were enrolled in this study. A 22-gauge intravenous (IV) catheter was inserted into a vein on the dorsum of the hand. Patients were randomly allocated to one of four groups to receive either saline or 0.5, 1, 2 mcg sufentartil in 2 ml volume. Thirty seconds after the intravenous (IV) injection of the pretreatment drug, 5 ml of 1% propofol at room temperature (Fresenius Kabi, Hamburg, Germany) was injected IV at rate of 0.5 ml/sec. Pain was assesed verbally and scored as none (0), mild (1), moderate (2), severe (3). Interventions: Prior injection of sufentanil or placebo Main Outcome Measures: Severity of PIP Results: Demographic data were comparable among four groups. Sufentanil at 1 and 2 mcg doses significantly decreased pain incidence when compared to the saline group (p < 0.05). Sufentanil 0.5 mcg had no effect.(p > 0.05). Although 2 mcg sufentanil decreased the incidence of PIP more than 1 mcg, there was no significant difference between these groups (p > 0.05). Conclusion: Sufentanil at one and 2 mcg doses reduced the incidence and severity of PIPen_US
dc.identifier.endpage124en_US
dc.identifier.issn0023-5776en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage121en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/27908
dc.identifier.volume44en_US
dc.identifier.wosWOS:000304683200007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherKUWAIT MEDICAL ASSOCen_US
dc.relation.ispartofKUWAIT MEDICAL JOURNALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectgeneral anesthesiaen_US
dc.subjectpainen_US
dc.subjectpropofolen_US
dc.subjectsufentanilen_US
dc.titleDetermining the Effect of Sufentanil on Propofol Injection Painen_US
dc.typeArticleen_US

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