Antimicrobial and Antioxidant Activities of Phenolic Compound Extracted from New Verbascum Species Growing in Turkey

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dc.contributor.authorSaltan, Fatma Zerrin
dc.contributor.authorSökmen, Münevver
dc.contributor.authorAkın, Mehtap
dc.contributor.authorSaraçoğlu, Hatice Taner
dc.contributor.authorGöktürk, Ramazan Süleyman
dc.contributor.authorAhmad, Manzoor
dc.contributor.authorAli, Mumtaz
dc.date.accessioned2020-03-26T18:13:47Z
dc.date.available2020-03-26T18:13:47Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate the antimicrobial and antioxidant potential of the aerial parts of four new Verbascum L. (Scrophulariaceae) species namely, Verbascum bellum Hub.-Mor., Verbascum detersile Boiss. & Heldr., Verbascum myriocarpum Boiss. & Heldr. and Verbascum pestalozzae Boiss., growing in Turkey. Plant materials were extracted with chloroform, ethylacetate and methanol for antimicrobial tests. These extracts were assayed against both gram-positive and gram-negative bacteria by the microdilution method. The minimum inhibitory concentrations of the Verbascum species varied between 150-0.59 mg/ml. In general, ethylacetate extract was effective for E. coli (ATCC 25922, 1.88 mg/ml). Ethyl acetate extract of V. pestalozzae exhibited the highest effect on P. aeroginosa (ATCC 29853, 0.59 mg/ml). The antioxidant capacity of the studied species was only tested with methanol extracts. Their antioxidant action was tested by DPPH and beta-carotene-linoleic acid methods. While V. pestalozzae (IC50=15 mu g/ml) exhibited the strongest activity in DPPH assay, V. detersile and V. pestalozzae provided an excellent inhibition effect (100% RAA) in the beta-caroten- linoleic acid system. HPLC analysis of methanol extracts was also carried out to determine the composition of the phenolic compounds responsible for the activity. Methanol extracts were also subjected to HPLC analysis to determine their phenolic compound profile.en_US
dc.description.sponsorshipAkdeniz University, Scientific Research Project UnitAkdeniz Universityen_US
dc.description.sponsorshipThe authors are grateful to Akdeniz University, Scientific Research Project Unit for financial support to collect plant samples.en_US
dc.identifier.endpage771en_US
dc.identifier.issn0253-5106en_US
dc.identifier.issue5en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage764en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26145
dc.identifier.volume33en_US
dc.identifier.wosWOS:000300381800028en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherCHEM SOC PAKISTANen_US
dc.relation.ispartofJOURNAL OF THE CHEMICAL SOCIETY OF PAKISTANen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleAntimicrobial and Antioxidant Activities of Phenolic Compound Extracted from New Verbascum Species Growing in Turkeyen_US
dc.typeArticleen_US

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