Biocompatible yogurt carbon dots: evaluation of utilization for medical applications

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dc.contributor.authorDinç, Saliha
dc.contributor.authorKara, Meryem
dc.contributor.authorKars, Meltem Demirel
dc.contributor.authorAykul, Fatmanur
dc.contributor.authorÇiçekci, Hacer
dc.contributor.authorAkkuş, Mehmet
dc.date.accessioned2020-03-26T19:34:06Z
dc.date.available2020-03-26T19:34:06Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIn this study, carbon dots (CDs) were produced from yogurt, a fermented milk product, via microwave-assisted process (800 W) in 30 min without using any additional chemical agents. Yogurt CDs had outstanding nitrogen and oxygen ratios. These dots were monodisperse and about 2 nm sized. The toxicological assessments of yogurt carbon dots in human cancer cells and normal epithelial cells and their fluorescence imaging in living cell system were carried out. Yogurt carbon dots had intense fluorescent signal under confocal microscopy and good fluorescence stability in living cell system. The resulting yogurt carbon dots exhibited high biocompatibility up to 7.1 mg/mL CD concentration which may find utilization in medical applications such as cellular tracking, imaging and drug delivery. Yogurt carbon dots have potential to be good diagnostic agents to visualize cancer cells which may be developed as a therapeutic carrier.en_US
dc.description.sponsorshipSelcuk UniversitySelcuk University [DPT-2009K121080]en_US
dc.description.sponsorshipThe authors would like to thank to Selcuk University Advanced Technology Research and Application Center for their research infrastructure. Laboratory equipments and facilities were funded by Selcuk University Research Fund with the project number DPT-2009K121080.en_US
dc.identifier.doi10.1007/s00339-017-1184-yen_US
dc.identifier.issn0947-8396en_US
dc.identifier.issn1432-0630en_US
dc.identifier.issue9en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s00339-017-1184-y
dc.identifier.urihttps://hdl.handle.net/20.500.12395/34840
dc.identifier.volume123en_US
dc.identifier.wosWOS:000407571500009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSPRINGERen_US
dc.relation.ispartofAPPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSINGen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleBiocompatible yogurt carbon dots: evaluation of utilization for medical applicationsen_US
dc.typeArticleen_US

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