To What Extent Should Para-Aortic Lymphadenectomy Be Carried Out for Surgically Staged Endometrial Cancer?

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dc.contributor.authorDoğan, Nasuh Utku
dc.contributor.authorGüngör, Tayfun
dc.contributor.authorKarslı, Fatih
dc.contributor.authorÖzgü, Emre
dc.contributor.authorBeşli, Mustafa
dc.date.accessioned2020-03-26T18:31:57Z
dc.date.available2020-03-26T18:31:57Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: To investigate the involvement of lymph nodes in para-aortic (PA) region particularly above and below the inferior mesenteric artery (IMA) in patients with endometrial cancer who had complete systemic pelvic and PA lymphadenectomy. Methods: A total of 165 consecutive patients with endometrial cancer surgically staged from January 2008 to March 2011 in the gynecologic oncology unit of a tertiary maternity center, Zekai Tahir Burak Hospital, Ankara, Turkey, were included retrospectively. All patients had complete pelvic and PA lymphadenectomy. Results: Nineteen women had any metastasis in pelvic and/or PA region. Twelve women (7.3%) had only pelvic, 5 women (3%) had both pelvic and PA, and 2 women had isolated PA metastasis. There were 6 patients (3.7%) with PA nodal metastasis above the IMA. Four patients with PA node involvement had positive nodes above the IMA without any metastasis below the IMA. In binary logistic regression analysis, PA metastasis above the IMA was associated with lymphovascular space invasion, pelvic metastasis, and tumor size. Conclusions: Isolated PA metastasis is rare in endometrial cancer. If pelvic nodes are involved, PA metastasis is likely, and PA lymphadenectomy should be performed up to renal vessels so as not to miss occult metastasis in higher regions particularly above the IMA.en_US
dc.identifier.citationDoğan, N. U., Güngör, T., Karslı, F., Özgü, E., Beşli, M., (2012). To What Extent Should Para-Aortic Lymphadenectomy Be Carried Out for Surgically Staged Endometrial Cancer?. International Journal of Gynecological Cancer, 22(4), 607-610. DOI: 10.1097/IGC.0b013e3182434adb
dc.identifier.doi10.1097/IGC.0b013e3182434adben_US
dc.identifier.endpage610en_US
dc.identifier.issn1048-891Xen_US
dc.identifier.issn1525-1438en_US
dc.identifier.issue4en_US
dc.identifier.pmid22546819en_US
dc.identifier.startpage607en_US
dc.identifier.urihttps://dx.doi.org/10.1097/IGC.0b013e3182434adb
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28579
dc.identifier.volume22en_US
dc.identifier.wosWOS:000303546100014en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorDoğan, Nasuh Utku
dc.institutionauthorGüngör, Tayfun
dc.institutionauthorKarslı, Fatih
dc.institutionauthorÖzgü, Emre
dc.institutionauthorBeşli, Mustafa
dc.language.isoenen_US
dc.publisherBMJ PUBLISHING GROUPen_US
dc.relation.ispartofInternational Journal of Gynecological Canceren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectEndometrial Canceren_US
dc.subjectSurgical Stagingen_US
dc.subjectPara-Aortic Lymphadenectomyen_US
dc.subjectInferior Mesenteric Arteryen_US
dc.titleTo What Extent Should Para-Aortic Lymphadenectomy Be Carried Out for Surgically Staged Endometrial Cancer?en_US
dc.typeArticleen_US

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