The effects of intracellular vitamin C concentrations on bovine neutrophils functions in vitro
Küçük Resim Yok
Tarih
1998
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ECOLE NATIONALE VETERINAIRE TOULOUSE
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, the effects of extracellular vitamin C on PMNL functions (phagocytic and microbicidal activity) and intracellular vitamin C levels were investigated. Neutrophils were obtained from eleven healthy Holstein heifers. Phagocytic and microbicidal activity of neutrophils were measured by fluorescent microscopic technique and intracellular vitamin C levels were determined with spectrophotometer. After first incubation (135 min., 37 degrees C) 149.76 %, 289.78 % and 462.76 % vitamin C increases were observed in PMNL, at 50, 150, 300 mu M/L of vitamin C, added to incubation media respectively. All the results compared to the controls, phagocytosis and microbicidal activity of PMNL increased by different vitamin C concentrations. A definite enhancement in PMNL functions observed in this study may have attributed to vitamin C supplemantation.
Açıklama
Anahtar Kelimeler
vitamin C, leucocyte functions, bovine
Kaynak
REVUE DE MEDECINE VETERINAIRE
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
149
Sayı
10
