Effects of zinc deficiency and supplementation on plasma leptin levels in rats
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Dosyalar
Tarih
2005
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
HUMANA PRESS INC
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The effects of zinc deficiency and supplementation on plasma leptin levels were studied in Sprague-Dawley rats. After 6 wk on a zinc-deficient diet containing 0.65 ppm Zn/g, the mean body weight was significantly lower than that of normal or zinc-supplemented rats, which showed no difference among them. The plasma leptin and zinc levels were lowest in zinc-deficient animals and highest in those that received a normal diet and daily intraperitioneal injections of 3 mg Zn/kg. These results indicate that zinc deficiency leads to a significant inhibition in plasma leptin levels, whereas zinc supplementation significantly increases plasma leptin.
Açıklama
Anahtar Kelimeler
zinc deficiency and supplementation, leptin, rat
Kaynak
BIOLOGICAL TRACE ELEMENT RESEARCH
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
104
Sayı
1
