Serum Levels of Lipids, Lipoproteins and Apolipoproteins in Patients with Coronary Artery Disease Documented by Angiography

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dc.contributor.authorKoçyiğit, Abdurrahim
dc.contributor.authorAkkuş, İdris
dc.contributor.authorVural, Hüseyin
dc.contributor.authorGök, Hasan
dc.contributor.authorÇağlayan, Osman
dc.contributor.authorDurmuş, Bilal
dc.contributor.authorÇelik, Mehmet
dc.contributor.authorMenekşe, Elif
dc.date.accessioned2020-03-26T16:25:00Z
dc.date.available2020-03-26T16:25:00Z
dc.date.issued1996
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractSerum Triglyceride (TG), total cholesterol (TC), phospholipid (PL), Apo A-I, Apo B, lipoprotein (a) (Lp(a)), high-density lipoprotein cholesterol (HDL-C,HDL2-C, HDL3-C), low density lipoprotein cholesterol (LDL-C) and free cholesterol (FC) levels of 108 subjects with and without coronary artery disease (CAD) documented by coronary angiography were investigated. Subjects were classified as normal and patients with CAD according to degree of vascular stenosis. Those with ? 50% stenosis in at least one major coronary artery branch were referred as patients with CAD. Patients consisted of 27 women aged 38-73 years and 44 men aged 31-72 years. Controls were 20 women aged 38-77 years and 17 men aged 38-77 years. Men with CAD had significantly higher plasma Lp(a), TC and LDL-C levels than the male controls. They also had significantly lower levels of Apo A-I, HDL-C and HDL2-C. Also, ratios of Apo B/Apo A-I and LDL-C/HDL-C were higher, whereas HDL2-C/HDL-C, HDL-C, TC and HDL2-C/HDL3-C ratios were lower than those of controls. On the other hand plasma Lp(a), Apo B, TC and FC levels of the women with CAD were significantly higher whereas HDL-2-C level was lower compared to the values of the female controls. Ratios of Apo B/Apo A-I and LDL-C/HDL-C were significantly higher, HDL2-C/HDL-C and HDL3-C and HDL2-C/HDL3-C ratio were lower than those of female controls. We concluded that Lp(a) is an independent risk factor for CAD and HDL2-C and HDL2-C/HDL3-C ratio are the best indicators of CAD both in men and women.en_US
dc.identifier.citationKocyigit, A., Akkus, I., Vural, H., Gok, H., Caglayan, O., Durmus, B., Celik, M., (1996). Serum Levels of Lipids, Lipoproteins and Apolipoproteins in Patients with Coronary Artery Disease Documented by Angiography. Turkish Journal of Medical Sciences, 26(2), 129.133.
dc.identifier.endpage133en_US
dc.identifier.issn1300-0144en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage129en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/16464
dc.identifier.volume26en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectApolipoproteinsen_US
dc.subjectCoronary Angiographyen_US
dc.subjectCoronary Artery Diseaseen_US
dc.subjectLipidsen_US
dc.subjectLipoproteinsen_US
dc.titleSerum Levels of Lipids, Lipoproteins and Apolipoproteins in Patients with Coronary Artery Disease Documented by Angiographyen_US
dc.typeArticleen_US

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