Investigation of the ecotoxicologic effect of pesticide industry wastewater on the pancreas and liver of rats

Basit Öğe Kaydı
dc.contributor.authorKalipci, Erkan
dc.contributor.authorOzdemir, Celalettin
dc.date.accessioned2020-03-26T18:15:01Z
dc.date.available2020-03-26T18:15:01Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIn this study, when the raw wastewater, which resulted from the manufacturing of 2,4-dichlorophenoxyacetic acid (2,4-D) dimethylamine salt and 2,4-D acid isooctylester herbicides in the factory, was discharged to the ecosystem without treatment, its ecotoxic effect on the pancreas and liver of rats was investigated. In this research, 16 Wistar Albino race male rats were grouped into two (Group 1-control, n = 8; Group 2-wastewater, n = 8) and were then used. The rats in Group 1 were fed by standard feed, while rats in Group 2 were fed by a diet including 200 mg/kg/day factory composite raw wastewater for 16 weeks, and dissection was carried out for all of them. In the research, it was determined that the body, liver and pancreas weights of rats were decreased when compared to the control group; however, there was no significant statistical difference (P > 0.05) between the two groups. In the histopathological investigation, on the other hand, it was determined that atypical cell focuses (ACF) (neoplastic variations) were observed in the liver and pancreas of rats in Group 2 and the quantitative analysis of the ACF was performed. In the livers of rats in Group 2, dilation in sinusoids close to the vein centralis and hydropic degeneration in parenchyma were observed when compared to the control group. Since there is a possibility that the neoplastic variations caused by this wastewater could be transformed into adenoma or carcinoma during long-term treatment, it also seems possible that it could be carcinogenic.en_US
dc.description.sponsorshipSelcuk UniversitySelcuk University [09101055]en_US
dc.description.sponsorshipThe authors gratefully acknowledge the Selcuk University Research Fund (BAP) for financially supporting this work (Project No: 09101055).en_US
dc.identifier.endpage2294en_US
dc.identifier.issn1684-5315en_US
dc.identifier.issue12en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage2290en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26584
dc.identifier.volume10en_US
dc.identifier.wosWOS:000290094900012en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherACADEMIC JOURNALSen_US
dc.relation.ispartofAFRICAN JOURNAL OF BIOTECHNOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subject2,4-Dichlorophenoxyacetic acid (2,4-D)en_US
dc.subjectherbicideen_US
dc.subjectwastewateren_US
dc.subjectatypical cell focusesen_US
dc.subjectpancreas and liveren_US
dc.subjectecotoxic effecten_US
dc.titleInvestigation of the ecotoxicologic effect of pesticide industry wastewater on the pancreas and liver of ratsen_US
dc.typeArticleen_US

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