Marine algae: A potential resource of anti-HSV molecules

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dc.authorid0000-0003-3962-8666
dc.authorid0000-0002-6398-0371
dc.authorid0000-0001-7205-7389
dc.authorid0000-0001-5728-6837
dc.authorid0000-0002-5125-3791
dc.authorid0000-0001-6548-7823
dc.authorid0000-0001-7447-6392
dc.contributor.authorMahomoodally, Mohamad Fawzi
dc.contributor.authorLobine, Devina
dc.contributor.authorRengasamy, Kannan R. R.
dc.contributor.authorGowrishankar, Shanmugaraj
dc.contributor.authorTewari, Devesh
dc.contributor.authorZengin, Gökhan
dc.contributor.authorKim, Doo Hwan
dc.contributor.authorSivanesan, Iyyakkannu
dc.date.accessioned2020-03-26T20:15:08Z
dc.date.available2020-03-26T20:15:08Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Fen Fakültesi, Biyoloji Bölümüen_US
dc.description.abstractHerpes simplex viruses (HSVs) are common human pathogens belonging to the subfamily alpha-herpesvirinae that trigger severe infections in neonates and immunocompromised patients. After primary infection, the HSVs establish a lifelong latent infection in the vegetative neural ganglia of their hosts. HSV infections contribute to substantial disease burden in humans as well as in newborns. Despite a fair number of drugs being available for the treatment of HSV infections, new, effective, and safe antiviral agents, exerting different mechanisms of action, are urgently required, mainly due to the increasing number of resistant strains. Accumulating pieces of evidence have suggested that structurally diverse compounds from marine algae possess promising anti-HSV potentials. Several studies have documented a variety of algal polysaccharides possessing anti-HSV activity, including carrageenan and fucan. This review aimed to compile previous anti-HSV studies on marine algae-derived compounds, especially sulfated polysaccharides, along with their mode of action, toward their development as novel natural anti-HSV agents for future investigations.en_US
dc.description.sponsorshipKU Research Professor Program of Konkuk Universityen_US
dc.description.sponsorshipThis article was supported by the KU Research Professor Program of Konkuk University.en_US
dc.identifier.citationMahomoodally, M. F., Lobine, D., Rengasamy, K. R., Gowrishankar, S., Tewari, D., Zengin, G., Kim, D. H., Sivanesan, I. (2019). Marine Algae: A Potential Resource of Anti-HSV Molecules. Processes, 7(12), 887.
dc.identifier.doi10.3390/pr7120887en_US
dc.identifier.issn2227-9717en_US
dc.identifier.issue12en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://dx.doi.org/10.3390/pr7120887
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37990
dc.identifier.volume7en_US
dc.identifier.wosWOS:000506635300025en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorZengin, Gökhan
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.relation.ispartofPROCESSESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectVirusen_US
dc.subjectNatural producten_US
dc.subjectGreen algaeen_US
dc.subjectBrown algaeen_US
dc.subjectRed algaeen_US
dc.subjectAntiviralen_US
dc.subjectHuman infectionsen_US
dc.subjectPhytochemicalsen_US
dc.subjectHerpesviridaeen_US
dc.subjectSulfated polysaccharidesen_US
dc.titleMarine algae: A potential resource of anti-HSV moleculesen_US
dc.typeArticleen_US

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