Üst GİS Kanamalarında Risk Faktörlerinin Prognoz Üzerine Etkisi
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Dosyalar
Tarih
2003
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmada amaç üst GİS kanamasına neden olan risk faktörlerinin ve uygulanan tedavi protokolünün prognoz açısından önemini değerlendirmekti. Yöntem: Çalışmaya prospektif olarak üst GiS kanaması şikayetleri ile acil kliniğe başvuran 37'si kadın, 78'i erkek, toplam 115 hasta alındı. Her bir hastanın gelişte risk faktörleri açısından anamnezi alındı ve fizik muayenesi yapıldı. Hastaların müracaat sırasındaki Hb, Htc, INR, SGOT, SGPT, LDH, üre, kreatinin ve kan şekeri düzeylerine bakıldı. Endoskopik inceleme yapıldı. Bulgular: Kaybedilen hastaların yaş ortalaması ile başvuru sırasındaki kan sekiri ve kreatinin değerleri taburcu edilen hastalarınkinden daha yüksek; diastolik kan basınçları ise daha düşük bulundu. Mortalite grubunda cerrahi tedavi oranı da daha yüksek idi. Taburcu edilen hastalar ile kaybedilen hastaların anamnezinde kronik karaciğer hastalığı, böbrek yetmezliği, önceden mevcut peptik ulkus hastalığı, steroid-nonsteroid ilaç kullanma hikayesi, sigara ve alkol alışkanlığı, başvuru sırasındaki sistolik kan basıncı, kalp hızı ile başvuru sırasındaki ortalama Hb, Htc, SGOT, SGPT, LDH, INR ve üre değerleri arasında anlamlı fark bulunamadı. Endoskopik tanı ile mortalité arasında ilişki bulunamadı. Üst GIS kanamalı hastalarda mortalitenin, hastanın yaşı, kan şekeri ve kreatinin düzeyi ile ilişkili olduğu saptandı. Sonuç: Üst GlS kanamalarında ileri yaş prognozu kötü yönde etkiler. 'Ayrıca hastaların gelişte ölçülen yüksek kan şekeri ve kreatinin değerleri kötü prognoza katkıda bulunur.
Objective: The aim of this study was to determine the effects of risk factors on prognosis of upper gastrointestinal bleeding and to find out the prognostic values of therapeutic protocols. Methods: Total 115 patients (37 women; 78 men) who were applied to emergency department with the gastrointestinal bleeding complaints were included into the study. Each patient was questioned for the risk factors, and each patient was physically examined. Blood samples were collected by venopuncture in order to determine the levels of hemoglobulin, hematocrit, prothrombin time, glucose, urea, creatinine, AST, ALT and LDH. Endoscopie evaluation was also made. Results: Mean age of patients who died was statistically higher than mean age of patients who were discharged at the end of the treatment. There was a statistically significant difference between patients who died and dismissed with respect to admission diastolic blood pressures, blood glucose, creatinine levels and surgical treatment. There was not any statistically significant difference between patients who died and dismissed chronic liver disease, renal failure, peptic ulcus disease, alcoholism, smoker, steroid-non steroid anti-inflammatory drug use, in admission pulse rate, sistolic blood pressures, mean hemoglobin-hematocrite values, AST, ALT, LDH, INR, urea levels. There was not any difference between endoscopie diagnosis and mortality. Conclusion: Prognosis in upper gastrointestinal bleedings worsens with the older age. In addition; admission higher blood glucose and creatinine values may contribute to the worse prognosis.
Objective: The aim of this study was to determine the effects of risk factors on prognosis of upper gastrointestinal bleeding and to find out the prognostic values of therapeutic protocols. Methods: Total 115 patients (37 women; 78 men) who were applied to emergency department with the gastrointestinal bleeding complaints were included into the study. Each patient was questioned for the risk factors, and each patient was physically examined. Blood samples were collected by venopuncture in order to determine the levels of hemoglobulin, hematocrit, prothrombin time, glucose, urea, creatinine, AST, ALT and LDH. Endoscopie evaluation was also made. Results: Mean age of patients who died was statistically higher than mean age of patients who were discharged at the end of the treatment. There was a statistically significant difference between patients who died and dismissed with respect to admission diastolic blood pressures, blood glucose, creatinine levels and surgical treatment. There was not any statistically significant difference between patients who died and dismissed chronic liver disease, renal failure, peptic ulcus disease, alcoholism, smoker, steroid-non steroid anti-inflammatory drug use, in admission pulse rate, sistolic blood pressures, mean hemoglobin-hematocrite values, AST, ALT, LDH, INR, urea levels. There was not any difference between endoscopie diagnosis and mortality. Conclusion: Prognosis in upper gastrointestinal bleedings worsens with the older age. In addition; admission higher blood glucose and creatinine values may contribute to the worse prognosis.
Açıklama
Anahtar Kelimeler
Genel ve Dahili Tıp, Üst Gastrointestinal Sistem, Peptik Ulkus, Antiinflamatuvarlar, Hemoraji, Risk Faktörleri, Upper Gastrointestinal System, Peptic Ulcus, Anti-İnflammatory Drugs, Bleeding, Risk Factors
Kaynak
Genel Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
13
Sayı
4
Künye
Bayır, A., Okumuş, M., Köstekçi, Ş. K., Şahin, T. K., (2003). Üst GİS Kanamalarında Risk Faktörlerinin Prognoz Üzerine Etkisi. Genel Tıp Dergisi, 13(4), 157-161.