Impact of different extraction solvents and techniques on the biological activities of Cirsium yildizianum (Asteraceae: Cynareae)

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dc.contributor.authorLlorent-Martinez, Eulogio J.
dc.contributor.authorZengin, Gökhan
dc.contributor.authorSinan, Kouadio Ibrahime
dc.contributor.authorPolat, Rıdvan
dc.contributor.authorCanlı, Deniz
dc.contributor.authorPicot-Allain, Marie Carene Nancy
dc.contributor.authorMahomoodally, Mohamad Fawzi
dc.date.accessioned2020-03-26T20:20:19Z
dc.date.available2020-03-26T20:20:19Z
dc.date.issued2020
dc.departmentSelçuk Üniversitesi, Fen Fakültesi, Biyoloji Bölümüen_US
dc.description.abstractSeveral Cirsium species have been used in folk medicine for the management of human ailments. However, there is a paucity of scientific data regarding their biological activity as in the case of the new species, C. yildizianum, from Anatolia, Turkey. The present study endeavours for the first time to appraise the antioxidant and enzyme inhibitory activity of C. yildizianum. The phytochemical profiles of C. yildizianum extracts obtained using homogeniser-assisted extraction (HAE), ultrasound-assisted extraction (UAE), Soxhlet extraction, maceration, decoction, and infusion, using methanol or water as extraction solvents, was determined by high-performance liquid chromatography with electrospray ionization mass spectrometric detection (HPLC-ESI-MSn) analysis. In all extracts, flavonoids were the most abundant compounds, particularly luteolin and apigenin glycosides. HAE methanol extract presented the highest phenolic (37.10 mg gallic acid equivalent/g) and flavonoid (46.78 mg rutin equivalent/g) contents. Likewise, HAE-methanol extract showed potent radical scavenging (40.76 and 68.13 mg Trolox equivalent [TE]/g, for DPPH and ABTS, respectively) and reducing properties (127.62 and 89.95 mg TE/g, for CUPRAC and FRAP, respectively). HAE-methanol extract showed inhibitory activity against acetylcholinesterase (AChE) (3.57 mg galantamine equivalent [GALAE]/g). UAE-methanol extract was a potent inhibitor of butrylcholinesterase (BChE) (2.72 mg GALAE/g) and tyrosinase (121.06 mg kojic acid equivalent/g) However, poor inhibition was recorded for enzymes targeted in the management of diabetes type II, namely alpha-amylase and alpha-glucosidase. On the other hand, potent metal chelating property was observed for water extracts. This study provides comprehensive scientific information on the phytochemical profile of C. yildizianum extracted using different procedures and extraction solvents, which might be considered as valuable baseline data for future bioproducts development.en_US
dc.identifier.citationLiorent-Martinez, E. J., Zengin, G., Sinan, K. I., Polat, R., Canlı, D., Picot-Allain, M. C. N., Mahomoodally, M. F. (2020). Impact of Different Extraction Solvents and Techniques on the Biological Activities of Cirsium yildizianum (Asteraceae: Cynareae). Industrial Crops & Products, 144, 1-8.
dc.identifier.doi10.1016/j.indcrop.2019.112033en_US
dc.identifier.issn0926-6690en_US
dc.identifier.issn1872-633Xen_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.indcrop.2019.112033
dc.identifier.urihttps://hdl.handle.net/20.500.12395/38556
dc.identifier.volume144en_US
dc.identifier.wosWOS:000510521700015en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorZengin, Gökhan
dc.institutionauthorSinan, Kouadio Ibrahime
dc.language.isoenen_US
dc.publisherELSEVIERen_US
dc.relation.ispartofINDUSTRIAL CROPS AND PRODUCTSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAnatoliaen_US
dc.subjectSoxhleten_US
dc.subjectDiabetesen_US
dc.subjectPhytochemicalen_US
dc.subjectPhytotherapyen_US
dc.titleImpact of different extraction solvents and techniques on the biological activities of Cirsium yildizianum (Asteraceae: Cynareae)en_US
dc.typeArticleen_US

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