Obez Çocuklarda Serum Lipidleri ve Lipid Peroksidasyonunun Araştırılması
Küçük Resim Yok
Tarih
2001
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Serum lipidleri ve lipid peroksidasyonunun araştırılması amacıyla, 7-12 (9.51 \pm 1.12) yaşları arasında 43 sağlıklı normal çocuk ile yaşları 7-12 (9.981.39) arasında 33 obez çocuğun serumlarında trigliserid, total kolesterol, serbest kolesterol, LDL-kolesterol , HDL-kolesterol, HDL2-kolesterol, HDL3-kolesterol, lipoprotein(a) ve lipid peroksidasyonu düzeylerine bakıldı ve sırasıyla obezlerde 120.1953.17 mg/dl, 172.53\pm30.07 mg/dl, 41.30 11.14 mg/dl, 103.51 28.09 mg/dl, 42.487.90 mg/dl, 8.044.75 mg/dl, 34.445.68 mg/ di, 19.4416.91 mg/dl, 3.981.84 nmol/ml; kontrol grubunda 78.3035.11 mg/dl, 151.42 \pm 23.84 mg/dl, 33.659.63 mg/dl, 88.8222.22 mg/dl, 47.036.13 mg/dl, 14.755.62 mg/ml, 32.274.31 mg/ml, 10.458.43 mg/ dl, 3.26\pm1.08 nmol/ml bulundu. Obezlerde trigliserid, total kolesterol, serbest kolesterol, LDL-kolesterol, lipoprotein(a), lipid peroksidasyonu değerlerinin (p0.001, p0.001, p0.005, p0.05, p0.005, p0.05) yüksek, HDL-kolesterol ve HDL2-kolesterol değerlerinin (p0.01, p0.001) düşük, lipid peroksidasyonu değerleri ile vücut kitle indeksi (body mass index) ve ağırlıkları arasında pozitif bir korelasyonun (r0.320, p0.05, r0.368, p0.05) olduğu görüldü. Obez çocukların ateroskleroz riski altında olabilecekleri ve izlemleri sırasında tüm bu parametrelerden yararlanılabileceği düşünüldü.
This study was carried out on 43 healthy children aged between 7-12 years (9.5±1.1) and 33 obese children aged between 7-12 years (10.01.4) to investigate serum levels of triglyceride total cholesterol, free cholesterol, LDL-cholesterol, HDL-cholesterol, HDL2-cholesterol, HDL3-cholesterol, lipoprotein(a) and lipid peroxidation. Results in the obese group were 120.2±53.2 mg/dl, 172.5±30.1 mg/dl, 41.3±11.1 mg/dl, 103.5±28.1 mg/dl, 42.5±7.9 mg/dl, 8.0±4.8 mg/dl, 34.4±5.7 mg/dl, 19.4±16.9 mg/dl, and 4.0±1.8 nmol/ml and in the control group, were 78.3\pm35.1 mg/dl, 151.4±23.8 mg/dl, 33.7±9.6 mg/dl, 88.8±22.2 mg/dl, 47.0±6.1 mg/dl, 14.8±5.6 mg/dl, 32.3±4.3 mg/dl, 10.5\pm8.4 mg/dl, and 3.3 \pm 1.1 nmol/ml, respectively. Serum levels of triglyceride total cholesterol, free cholesterol, LDL-cholesterol, lipoprotein(a) and lipid peroxidation of the obese group were significantly increased, and of HDL-cholesterol and HDL2-cholesterol decreased (p<0.001, p<0.001, p<0.005, p<0.05, p<0.005, p<0.05, p<0.01, p<0.001, respectively). A positive correlation was detected between lipid peroxidation values and body mass index (Quatelet index) and body weight (r0.320, p<0.05, r0.368, p<0.05, respectively). Results of the present study suggest that obese children might be under the risk of atherosclerosis.
This study was carried out on 43 healthy children aged between 7-12 years (9.5±1.1) and 33 obese children aged between 7-12 years (10.01.4) to investigate serum levels of triglyceride total cholesterol, free cholesterol, LDL-cholesterol, HDL-cholesterol, HDL2-cholesterol, HDL3-cholesterol, lipoprotein(a) and lipid peroxidation. Results in the obese group were 120.2±53.2 mg/dl, 172.5±30.1 mg/dl, 41.3±11.1 mg/dl, 103.5±28.1 mg/dl, 42.5±7.9 mg/dl, 8.0±4.8 mg/dl, 34.4±5.7 mg/dl, 19.4±16.9 mg/dl, and 4.0±1.8 nmol/ml and in the control group, were 78.3\pm35.1 mg/dl, 151.4±23.8 mg/dl, 33.7±9.6 mg/dl, 88.8±22.2 mg/dl, 47.0±6.1 mg/dl, 14.8±5.6 mg/dl, 32.3±4.3 mg/dl, 10.5\pm8.4 mg/dl, and 3.3 \pm 1.1 nmol/ml, respectively. Serum levels of triglyceride total cholesterol, free cholesterol, LDL-cholesterol, lipoprotein(a) and lipid peroxidation of the obese group were significantly increased, and of HDL-cholesterol and HDL2-cholesterol decreased (p<0.001, p<0.001, p<0.005, p<0.05, p<0.005, p<0.05, p<0.01, p<0.001, respectively). A positive correlation was detected between lipid peroxidation values and body mass index (Quatelet index) and body weight (r0.320, p<0.05, r0.368, p<0.05, respectively). Results of the present study suggest that obese children might be under the risk of atherosclerosis.
Açıklama
Anahtar Kelimeler
Genel ve Dahili Tıp, Pediatri
Kaynak
Çocuk Sağlığı ve Hastalıkları Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
44
Sayı
2
Künye
Aköz, M., Karaeren, Z., Gültekin, F., Gürbilek, M., Mehmetoğlu, İ., Vatansev, H., Koç, H., (2001). Obez Çocuklarda Serum Lipidleri Ve Lipid Peroksidasyonunun Araştırılması. Çocuk Sağlığı ve Hastalıkları Dergisi, 44(2), 135-140.
