The Incidence of Cystic Fibrosis in the Central Region of Anatolia in Turkey Between 2015 and 2016
Yükleniyor...
Dosyalar
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Cystic fibrosis is the most common metabolic chronic disease among European Caucasian children. Cystic fibrosis incidence in Northern Europeans countries is approximately 1 in 3000 births while the worldwide prevalence varies considerably.Aims: To determine the incidence of cystic fibrosis in the central region of Anatolia in Turkey using the newborn screening program data.Study Design: Cross-sectional study.Methods: We used the records of the newborn screening program which is implemented by the Konya and Kayseri Provincial Health Directories. Between January 2015 and December 2016, there were a total of 119006 live births in Konya and Kayseri. The newborn screening test was applied to all these babies.Results: During this period, there were 22 live born babies diagnosed with cystic fibrosis in Konya with an incidence of 2.9 per 10000 live births and 13 live born babies diagnosed with cystic fibrosis in Kayseri with an incidence of 2.8 per 10000 live births. In genetic of 30 patients, fifteen patients were homozygous, and 15 patients were a compound heterozygote. Twenty-one different gene variants were detected and the most common mutation was F508del (17/30)Conclusion: We found the incidence of cystic fibrosis in central Anatolia similar to northern European countries.
Açıklama
Anahtar Kelimeler
Cerrahi, Genel ve Dahili Tıp, Klinik Nöroloji, Sağlık Bilimleri ve Hizmetleri, Temel Sağlık Hizmetleri, Tıbbi Araştırmalar Deneysel, Tıbbi İnformatik
Kaynak
Balkan Medical Journal
WoS Q Değeri
Scopus Q Değeri
Cilt
36
Sayı
3
Künye
Hangül, M., Pekcan, S., Köse, M., Acıcan, D., Şahlar, T. E., Erdoğan, M., Kendirci, M., Güney, D., Öznavruz, H., Demir, O., Ercan, Ö., Göçlü, F. (2019). The Incidence of Cystic Fibrosis in the Central Region of Anatolia in Turkey Between 2015 and 2016, Balkan Medical Journal, 36(3), 179-183.
