The Incidence of Cystic Fibrosis in the Central Region of Anatolia in Turkey Between 2015 and 2016

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dc.contributor.authorHangül, Melih
dc.contributor.authorPekcan, Sevgi
dc.contributor.authorKöse, Mehmet
dc.contributor.authorAcıcan, Deniz
dc.contributor.authorŞahlar, Tuba Esra
dc.contributor.authorErdoğan, Murat
dc.contributor.authorKendirci, Mustafa
dc.contributor.authorGüney, Deniz
dc.contributor.authorÖznavruz, Hasan
dc.contributor.authorDemir, Osman
dc.contributor.authorErcan, Ömür
dc.contributor.authorGöçlü, Fatma
dc.date.accessioned2020-03-26T20:11:59Z
dc.date.available2020-03-26T20:11:59Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi en_US
dc.description.abstractBackground: Cystic fibrosis is the most common metabolic chronic disease among European Caucasian children. Cystic fibrosis incidence in Northern Europeans countries is approximately 1 in 3000 births while the worldwide prevalence varies considerably.Aims: To determine the incidence of cystic fibrosis in the central region of Anatolia in Turkey using the newborn screening program data.Study Design: Cross-sectional study.Methods: We used the records of the newborn screening program which is implemented by the Konya and Kayseri Provincial Health Directories. Between January 2015 and December 2016, there were a total of 119006 live births in Konya and Kayseri. The newborn screening test was applied to all these babies.Results: During this period, there were 22 live born babies diagnosed with cystic fibrosis in Konya with an incidence of 2.9 per 10000 live births and 13 live born babies diagnosed with cystic fibrosis in Kayseri with an incidence of 2.8 per 10000 live births. In genetic of 30 patients, fifteen patients were homozygous, and 15 patients were a compound heterozygote. Twenty-one different gene variants were detected and the most common mutation was F508del (17/30)Conclusion: We found the incidence of cystic fibrosis in central Anatolia similar to northern European countries.en_US
dc.identifier.citationHangül, M., Pekcan, S., Köse, M., Acıcan, D., Şahlar, T. E., Erdoğan, M., Kendirci, M., Güney, D., Öznavruz, H., Demir, O., Ercan, Ö., Göçlü, F. (2019). The Incidence of Cystic Fibrosis in the Central Region of Anatolia in Turkey Between 2015 and 2016, Balkan Medical Journal, 36(3), 179-183.
dc.identifier.doi10.4274/balkanmedj.galenos.2018.2018.1332en_US
dc.identifier.endpage183en_US
dc.identifier.issn2146-3123en_US
dc.identifier.issn2146-3131en_US
dc.identifier.issue3en_US
dc.identifier.startpage179en_US
dc.identifier.urihttps://dx.doi.org/10.4274/balkanmedj.galenos.2018.2018.1332
dc.identifier.urihttp://www.trdizin.gov.tr/publication/paper/detail/TXpFNE9UTXhNUT09
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37294
dc.identifier.volume36en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorÖznavruz, Hasan
dc.language.isoenen_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCerrahien_US
dc.subjectGenel ve Dahili Tıpen_US
dc.subjectKlinik Nörolojien_US
dc.subjectSağlık Bilimleri ve Hizmetlerien_US
dc.subjectTemel Sağlık Hizmetlerien_US
dc.subjectTıbbi Araştırmalar Deneyselen_US
dc.subjectTıbbi İnformatiken_US
dc.titleThe Incidence of Cystic Fibrosis in the Central Region of Anatolia in Turkey Between 2015 and 2016en_US
dc.typeArticleen_US

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