A new perylene bisimide-armed calix[4]-aza-crown as "turn on" fluorescent sensor for Hg2+ ion and its application to living cells
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ELSEVIER SCIENCE SA
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
We report the design and synthesis of a new perylene bisimide derivative containing calix[4]arene units (PB-CX[4]) as "turn on" fluorescent sensor for Hg2+ ion determination. PB-CX[4] showed highly selective and sensitive "turn-on" fluorescent responses toward Hg2+ ion based on photoinduced electron transfer (PET) mechanism in DMF/H2O (v/v, 9515). The binding analysis using a Job plot suggested that PB-CX[4] formed a 1:2 complex with He. The association constant (K) of PB-CX[4]-Hg2+ complex was found to be 1.66 x 10(9) M-7, with a detection limit of 5.56 x 10(-7) M. In addition, possible utilization of PB-CX[4] as bio-imaging fluorescent probe to detect Hg2+ in human colon cancer cell lines was also observed by confocal fluorescence microscopy. (C) 2015 Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Perylene, Calixarene, Fluorescent, Turn on, Mercury
Kaynak
SENSORS AND ACTUATORS B-CHEMICAL
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
220
