Synthesis and application of novel magnetite nanoparticle based azacrown ether for protein recognition
Küçük Resim Yok
Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
POLYMER SOC KOREA
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
This article is the first report showing the human serum albumin (HSA) binding studies by using a new magnetite nanoparticle containing azacrown ether moieties via solid-liquid extraction process. The structure of the newly prepared magnetite nanoparticle was clarified by using attenuated total reflectance (ATR) infrared spectroscopy, scanning electron microscopy (SEM), UV-vis and elemental analysis. Analytic results indicated that modification of the surface of the magnetite nanoparticles with azacrown ether derivative was successfully carried out. The protein binding studies exhibited that the modified magnetite nanoparticles could be efficiently used for the binding of the human serum albumin (HSA) in aqueous solutions via non-covalent interaction between crown ether cavity and amino group of the protein.
Açıklama
Anahtar Kelimeler
crown ether, human serum albumin (HSA), magnetite nanoparticle, protein binding, silica gel
Kaynak
MACROMOLECULAR RESEARCH
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
21
Sayı
9
