Synthesis and application of novel magnetite nanoparticle based azacrown ether for protein recognition
No Thumbnail Available
Date
2013
Journal Title
Journal ISSN
Volume Title
Publisher
POLYMER SOC KOREA
Access Rights
info:eu-repo/semantics/closedAccess
Abstract
This article is the first report showing the human serum albumin (HSA) binding studies by using a new magnetite nanoparticle containing azacrown ether moieties via solid-liquid extraction process. The structure of the newly prepared magnetite nanoparticle was clarified by using attenuated total reflectance (ATR) infrared spectroscopy, scanning electron microscopy (SEM), UV-vis and elemental analysis. Analytic results indicated that modification of the surface of the magnetite nanoparticles with azacrown ether derivative was successfully carried out. The protein binding studies exhibited that the modified magnetite nanoparticles could be efficiently used for the binding of the human serum albumin (HSA) in aqueous solutions via non-covalent interaction between crown ether cavity and amino group of the protein.
Description
Keywords
crown ether, human serum albumin (HSA), magnetite nanoparticle, protein binding, silica gel
Journal or Series
MACROMOLECULAR RESEARCH
WoS Q Value
Q2
Scopus Q Value
Q2
Volume
21
Issue
9
