Interaction of MC3T3-E1 cells with titanium implants

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dc.contributor.authorKorkusuz, Petek
dc.contributor.authorHakki, Sema S.
dc.contributor.authorPurali, Nuhan
dc.contributor.authorGorur, Ilker
dc.contributor.authorOnder, Ercuement
dc.contributor.authorNohutcu, Rahime
dc.contributor.authorKoc, Nursen
dc.date.accessioned2020-03-26T17:27:04Z
dc.date.available2020-03-26T17:27:04Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectives The aim of the present study was to evaluate in-vitro MC3T3-E1 preosteoblastic cell osseointegration on surfaces of polished, sand-blasted (smooth and rough) and sodium titanate coated titanium alloys. Materials and methods MC3T3-E1 cell proliferation and mineralization was assessed comparatively on polished, sand-blasted (smooth and rough) and sodium titanate coated titanium alloys. Cell morphology, attachment and proliferation were also comparatively evaluated using confocal (CM) and scanning electron microscopy (SEM). Results All implants Used in this study were biocompatible. Cells started to attach on the surfaces of the implants following exposure to the in vitro medium for 3 days. The cells were viable and metabolically active as observed by CM. Cell Population increased exponentially from day 3 to day 22. Proliferation rate was highest on polished surfaces and lowest on sodium titanate-coated surfaces. In contrast, mineralized nodules were numerous on sand-blasted and sodium titanate-coated Surfaces when compared to the polished ones on day 30. Conclusion This study demonstrated that sand-blasting and sodium titanate coating provided by NaOH favored the attachment, mineralization and early differentiation of osteoblasts on titanium alloys.en_US
dc.description.sponsorshipTechnical and Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [105-S-097 (SBAG 3130)]en_US
dc.description.sponsorshipTechnical and Research Council of Turkey (Grant No: 105-S-097 (SBAG 3130)) Supported this study. Cell culture facilites in Research Center of Faculty Of Dentistry, Selcuk University was used.en_US
dc.identifier.endpage90en_US
dc.identifier.issn1305-8282en_US
dc.identifier.issn1309-0313en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage84en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22462
dc.identifier.volume19en_US
dc.identifier.wosWOS:000258609600007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTURKISH JOINT DISEASES FOUNDATIONen_US
dc.relation.ispartofEKLEM HASTALIKLARI VE CERRAHISI-JOINT DISEASES AND RELATED SURGERYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjecttitaniumen_US
dc.subjectimplanten_US
dc.subjectboneen_US
dc.subjectosteoblast cell cultureen_US
dc.subjectMC3T3-E1en_US
dc.subjectscanning electron microscopyen_US
dc.subjectconfocal microscopyen_US
dc.titleInteraction of MC3T3-E1 cells with titanium implantsen_US
dc.typeArticleen_US

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