Effect of garlic oil on erythrocyte membrane phospholipid fractions in hypercholesterolaemic dogs

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dc.contributor.authorKeskin, E
dc.contributor.authorDurgun, Z
dc.contributor.authorKocabatmaz, M
dc.contributor.authorTras, B
dc.contributor.authorEryavuz, A
dc.contributor.authorDonmez, N
dc.date.accessioned2020-03-26T16:25:22Z
dc.date.available2020-03-26T16:25:22Z
dc.date.issued1997
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractWe studied the effects of a cholesterol diet alone and of a cholesterol diet plus garlic oil on erythrocyte membrane phospholipid fractions in 10 adult mongrel dogs. The animals were fed the control diet plus 0.5% cholesterol for 6 weeks and the control diet containing 5% cholesterol plus garlic oil at 20 mg kg(-1) body weight daily for the last 3 weeks of the experiment. Feeding with the cholesterol-rich diet resulted in significant (p < 0.05) increases in erythrocyte membrane lipids. The administration of garlic oil not only prevented the increases but also reduced the levels of phospholipid and cholesterol, though not significantly. Although phospholipid (PL) fractions showed fluctuations with the cholesterol feeding and garlic oil administration, there was no significant difference between the sampling times. In conclusion, further studies are necessary on the effect of garlic on the membrane PL fractions because of the importance of PL in all aspects of membrane physiology from anion transport to regulation of cell structure.en_US
dc.identifier.endpage763en_US
dc.identifier.issn0269-8951en_US
dc.identifier.issue11en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage761en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/16576
dc.identifier.volume25en_US
dc.identifier.wosWOS:A1997YH33500013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherLIPPINCOTT WILLIAMS & WILKINSen_US
dc.relation.ispartofMEDICAL SCIENCE RESEARCHen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjecthypercholesterolaemiaen_US
dc.subjectgarlic oilen_US
dc.subjecterythrocyte membraneen_US
dc.subjectphospholipid fractionsen_US
dc.titleEffect of garlic oil on erythrocyte membrane phospholipid fractions in hypercholesterolaemic dogsen_US
dc.typeArticleen_US

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