Screening of Possible In Vitro Neuroprotective, Skin Care, Antihyperglycemic, and Antioxidative Effects of Anchusa undulata L. subsp. hybrida (Ten.) Coutinho from Turkey and Its Fatty Acid Profile
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Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
TAYLOR & FRANCIS INC
Access Rights
info:eu-repo/semantics/closedAccess
Abstract
The aim of this work was to determine antioxidant capacities, neuroprotective, skin care, antidiabetic effects, and fatty acid composition of Anchusa undulata subsp. hybrida. The antioxidant activity was screened by four different test systems including total antioxidant, antiradical, reducing power, and metal chelating activities. Neuroprotective potential was determined by anticholinesterase inhibitor assay. Tyrosinase inhibitory activity was tested to detect skin care effect. Antidiabetic effects were evaluated with alpha-amylase and alpha-glucosidase inhibitory assays. Inhibitory activities on acetycholinesterase, butyrylcholinesterase, tyrosinase, alpha-amylase, and alpha-glucosidase enzymes were observed as 2.238 and 1.239 mu mol GALAEs/g, 0.339 mmol KAEs/g, 0.193, and 0.219 mmol ACEs/g extract, respectively. Amount of total phenolics and flavonoids were found as 80.34 mu g GAEs/mg and 25.09 mu g QEs/mg in the extract, respectively. Twenty-three fatty acids were found in the aerial parts, being oleic acid (24.30 g/100 g of total fatty acids) the most abundant, followed by linoleic (21.19 g/100 g of total fatty acids) and palmitic acids (17.50 g/100 g of total fatty acids).
Description
Keywords
Antihyperglycemic, Antioxidants, Fatty acids, Neuroprotective activity, Phenolic content, Boraginaceae
Journal or Series
INTERNATIONAL JOURNAL OF FOOD PROPERTIES
WoS Q Value
Q2
Scopus Q Value
Q2
Volume
18
Issue
7
