Heparin-Induced Thrombocytopenia Association with Impaired Liver Function Tests

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dc.contributor.authorArslan, Derya
dc.contributor.authorGuvenc, Osman
dc.contributor.authorCimen, Derya
dc.contributor.authorOran, Bulent
dc.date.accessioned2020-03-26T19:24:28Z
dc.date.available2020-03-26T19:24:28Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractHeparin-induced thrombocytopenia is an intensely procoagulant disorder and carries significant morbidity and mortality. However, the elevations in serum aminotransferases are characteristically asymptomatic and reversible with treatment termination. The serious liver injury due to heparins has not been reported but liver function should be monitored closely since potential severe liver damage with hepatocyte necrosis can occur. In this case report, we present a one-year-old male patient who developed a left lower extremity arterial thrombosis following an pulmonary artery banding procedure. Our case was taking unfractionated heparin for anticoagulation. On the third day of heparin therapy, routine blood analysis revealed deranged hepatic function tests and thrombocytopenia. Unfractionated heparin treatment was discontinued and he was treated with therapeutic doses of low-molecular-weight heparin for arterial thrombosis. His platelet count and liver function tests had normalised 2 weeks later.en_US
dc.identifier.doi10.4328/JCAM.1745en_US
dc.identifier.endpage109en_US
dc.identifier.issn1309-0720en_US
dc.identifier.issn1309-2014en_US
dc.identifier.pmid#YOKen_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage107en_US
dc.identifier.urihttps://dx.doi.org/10.4328/JCAM.1745
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33659
dc.identifier.volume7en_US
dc.identifier.wosWOS:000396411700009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherDERMAN MEDICAL PUBLen_US
dc.relation.ispartofJOURNAL OF CLINICAL AND ANALYTICAL MEDICINEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectHeparin-induced Thrombocytopeniaen_US
dc.subjectLiver Damageen_US
dc.subjectArterial Thrombosisen_US
dc.subjectChildrenen_US
dc.titleHeparin-Induced Thrombocytopenia Association with Impaired Liver Function Testsen_US
dc.typeArticleen_US

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