The distrubition of community-acquired gram negative microorganisms isolated from the urine samples of children, and the evaluation of increase in antibiotic resistance between the years 2003-2010

Basit Öğe Kaydı
dc.contributor.authorGuner, Sukru Nail
dc.contributor.authorGokturk, Bahar
dc.contributor.authorBayrakci, Umut Selda
dc.contributor.authorBaskin, Esra
dc.date.accessioned2020-03-26T18:31:35Z
dc.date.available2020-03-26T18:31:35Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAim: Appropriate antibiotic use for urinary tract infection (UTI) will provide protection against antibiotic resistance and complications including renal parenchimal damage and reflux nephropathy which may occur in the future. This study aimed to show the distrubition of community-acquired gram negative microorganisms in the region of Konya and the change in antibiotic resistance rates in time. Material and Method: Patients between 0 and 17 years of age with a positive urine culture between July 2003 and January 2010 were included in the study. 2544 positive cultures were obtained from a total of 1742 patients. Results: : Female patients costituted 57.6 % of the patients who had positive urine culture. Microorganisms isolated from infected female and male patients included E coli (76.1 and 41.9%), Klebsiella spp (13.7 and 24.3%), Proteus spp (6.9 and 28.4%) and the others (3.4 and 5.2%). E.coli, Klebsiella and Proteus species were found to be sensitive to carbapenems, aminoglycosides, quinolones and third generation cephalosporines. High trimetoprim-sulphametoxasol (TMP-SM) resistance in the E.coli and Proteus groups (48.2%-48.5%) and high ampicillin resistance (68.9-88.2%) in the E.coli and Klebsiella groups were remarkable. For all three microorganisms an amikacin sensitivity of 100% was found. When antibiotic sensitivities were compared between the periods of 2003-2006 and 2006-2010, resistance rates of microorganisms against many antibiotics were found to be increased significantly. Conclusions: These data suggested that the microorganisms causing UTI were susceptible to aminoglycosides and third generation cephalosporins. The apparent increase in the resistance rates over a relatively short period was a precarious circumstance. Trimethoprim-sulphamethoxazole and ampicilline should not be the first choice for treatment of UTI because of high resistance rates. (Turk Arch Ped 2012; 47: 107-13)en_US
dc.identifier.doi10.4274/tpa.721en_US
dc.identifier.endpage113en_US
dc.identifier.issn1306-0015en_US
dc.identifier.issn1308-6278en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage107en_US
dc.identifier.urihttps://dx.doi.org/10.4274/tpa.721
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28485
dc.identifier.volume47en_US
dc.identifier.wosWOS:000304232900008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherAVESen_US
dc.relation.ispartofTURK PEDIATRI ARSIVI-TURKISH ARCHIVES OF PEDIATRICSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAntibiotic resistanceen_US
dc.subjectcommunity acquired urinary tract infectionen_US
dc.subjectchilden_US
dc.titleThe distrubition of community-acquired gram negative microorganisms isolated from the urine samples of children, and the evaluation of increase in antibiotic resistance between the years 2003-2010en_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
28485.pdf
Boyut:
107.61 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu