Calix[4]arene derivatives as dopamine hosts in electrochemical sensors

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dc.contributor.authorKurzatkowska, Katarzyna
dc.contributor.authorSayın, Serkan
dc.contributor.authorYılmaz, Mustafa
dc.contributor.authorRadecka, Hanna
dc.contributor.authorRadecki, Jerzy
dc.date.accessioned2020-03-26T19:01:10Z
dc.date.available2020-03-26T19:01:10Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIn this work, we introduce the use of an electrochemical sensor based on ion-channel mechanism in order to investigate the interaction between different-functionalized calixarene mercaptoalkyl derivatives and dopamine at the aqueous/organic interface. Three different calix[4]arene derivatives, functionalized with mercaptoalky groups at the upper-rim of calix[4]arene, were synthesized, and their structures were characterized by FTIR, H-1 and C-13 NMR spectroscopy, and elemental analysis techniques. Moreover, these calixarene-mercaptoalkyl derivatives were grafted onto gold electrode surface by covalent Au-S bound. To elucidate the functional groups' influences on the signal generation mechanism, three different-substituted calixarene-mercaptoalkyl derivatives, with an opposite arrangement of the functional moieties and mercaptoalkyl groups at the lower and the upper rim of the calixarene, were interacted for the first time with dopamine. The formation of a supramolecular complex between the calix[4]arene host and the dopamine guest were confirmed by Osteryoung square-wave voltammetry with [Ru(NH3)6]Cl-3 as an redox active marker. The proposed electrochemical sensors were suitable for the determination of dopamine in the concentration range from 1.0 x 10(-11) M to 1.0 x 10(-6) M. In order to demonstrate the applicability of the sensors proposed, the electrochemical determination of dopamine in the presence of ascorbic acid and uric acid were checked. It was proved that these interferences did not influence on dopamine determination. The detection limit was estimated as 4.9 pM. (C) 2015 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipCOST Action "Supramolecular Chemistry in Water" [CM10005]; Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn, Poland; Scientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [111T027]; Research Foundation of Selcuk University (BAP)Selcuk Universityen_US
dc.description.sponsorshipThis work was supported by COST Action CM10005 "Supramolecular Chemistry in Water" and by statutory fund of Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn, Poland and the Scientific and Technological Research Council of Turkey (TUBITAK grant no. 111T027) and the Research Foundation of Selcuk University (BAP).en_US
dc.identifier.doi10.1016/j.snb.2015.04.110en_US
dc.identifier.endpage121en_US
dc.identifier.issn0925-4005en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage111en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.snb.2015.04.110
dc.identifier.urihttps://hdl.handle.net/20.500.12395/31901
dc.identifier.volume218en_US
dc.identifier.wosWOS:000355919900016en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE SAen_US
dc.relation.ispartofSENSORS AND ACTUATORS B-CHEMICALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCalixareneen_US
dc.subjectSynthesisen_US
dc.subjectDopamineen_US
dc.subjectMolecular recognitionen_US
dc.subjectIon-channel mimetic sensorsen_US
dc.subjectVoltammetric sensorsen_US
dc.titleCalix[4]arene derivatives as dopamine hosts in electrochemical sensorsen_US
dc.typeArticleen_US

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