Development of a spectrofluorimetric method for determination of albendazole in tablets

dc.contributor.authorKuecuekkolbasi, Semahat
dc.contributor.authorGuenduez, Beniz
dc.contributor.authorKilic, Esma
dc.date.accessioned2020-03-26T17:26:39Z
dc.date.available2020-03-26T17:26:39Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIn this study a spectrofluorimetric method was developed to determine drug active compound in the tablets for albendazole (ABZ). For this aim, fluorescence spectra of albendazolee drug active compound in various solvents were taken, it was determined that the most suitable solvent was chloroform and excitation (lambda(ex)) and emission (lambda(em)) wavelength in a row was 360nm and 440nm in this solvent. Calibration graphics were drawn and shown linear at 0-2.5mg/l concentration range (R-2=0.9993). Albendazole quantity in the andazol tablets was determined from directly calibration graphs and with standard addition method. Results obtained with developed spectrofluorimetric method were compared with standard USP method and it was found no difference between two methods within 95% confidence limits. It was determined that proposed method was easy and highly accuracy method to be able to use in routine albendazole analyze for the quality control.en_US
dc.identifier.doi10.1080/00032710701746857en_US
dc.identifier.endpage118en_US
dc.identifier.issn0003-2719en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage104en_US
dc.identifier.urihttps://dx.doi.org/10.1080/00032710701746857
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22322
dc.identifier.volume41en_US
dc.identifier.wosWOS:000252761900009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS INCen_US
dc.relation.ispartofANALYTICAL LETTERSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectalbendazoleen_US
dc.subjectspectrofluorimetric determinationen_US
dc.subjectpharmaceuticalsen_US
dc.titleDevelopment of a spectrofluorimetric method for determination of albendazole in tabletsen_US
dc.typeArticleen_US

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