Diagnostic Value of Clinical and Laboratory Findings in Childhood Meningitis

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dc.contributor.authorEmiroglu M.
dc.contributor.authorKesli R.
dc.contributor.authorKilicaslan M.
dc.date.accessioned2020-03-26T20:20:46Z
dc.date.available2020-03-26T20:20:46Z
dc.date.issued2020
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective Acute meningitis in childhood is a serious infectious disease that requires immediate medical assessment to ensure appropriate treatment and healthy outcomes. The aim of this retrospective study was to evaluate clinical and laboratory findings in the diagnosis of acute meningitis in children. Materials and Methods Between February 2011 and March 2013, 258 children aged between 1 month and 18 years who were admitted to Konya Training and Research Hospital, Turkey, with clinically suspected meningitis and undergoing lumbar puncture were enrolled in the study. Patient charts were reviewed using a standardized data collection tool. Fifty-nine patients were excluded because of incomplete data or because they did not meet the enrollment criteria. Further statistical analysis was conducted on the remaining 199 patients. The diagnostic values of clinical and laboratory findings for acute meningitis were investigated. IBM SPSS 21.0 for Windows was used for the statistical analysis. Results Of the 199 patients (61.3% male; median age: 24 months), 101 (50.8%) were diagnosed with meningitis. A definitive diagnosis of bacterial meningitis was made in 16 patients, while 5 patients had probable bacterial meningitis. In addition, 80 patients diagnosed as aseptic meningitis and 47 of these patients had human enterovirus meningitis. Headache was more common in patients with meningitis. In patients without meningitis, the most common complaints were seizures or seizures accompanied by fever. Erythrocyte sedimentation rates (ESR), levels of cerebrospinal fluid protein, and cell counts in cerebrospinal fluid examinations were higher in the meningitis group. C-reactive protein, ESR, and procalcitonin higher than 22.55 mg/L, 36.5 mm/hour, and 6.795 mg/mL, respectively, indicated bacterial meningitis. Conclusion Our results showed that a combination of clinical and laboratory markers could facilitate recognition of bacterial meningitis in children. © 2020 by Georg Thieme Verlag KG, Stuttgart. New York.en_US
dc.identifier.doi10.1055/s-0039-3400960en_US
dc.identifier.endpage85en_US
dc.identifier.issn1305-7707en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage79en_US
dc.identifier.urihttps://dx.doi.org/10.1055/s-0039-3400960
dc.identifier.urihttps://hdl.handle.net/20.500.12395/38664
dc.identifier.volume15en_US
dc.identifier.wosWOS:000518695400003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlagen_US
dc.relation.ispartofJournal of Pediatric Infectious Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectchildhooden_US
dc.subjectclinical findingsen_US
dc.subjectlaboratory findingsen_US
dc.subjectmeningitisen_US
dc.titleDiagnostic Value of Clinical and Laboratory Findings in Childhood Meningitisen_US
dc.typeArticleen_US

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