Lathyrus Aureus and Lathyrus Pratensis: Characterization of Phytochemical Profiles by Liquid Chromatography-Mass Spectrometry, and Evaluation of Their Enzyme Inhibitory and Antioxidant Activities

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dc.authorid0000-0002-8901-6484
dc.authorid0000-0002-8537-3978
dc.authorid0000-0002-7795-8482
dc.authorid0000-0003-4771-2489
dc.contributor.authorLlorent-Martinez, Eulogio J.
dc.contributor.authorOrtega-Barrales, Pilar
dc.contributor.authorZengin, Gökhan
dc.contributor.authorUysal, Şengül
dc.contributor.authorCeylan, Ramazan
dc.contributor.authorGüler, Gökalp Özmen
dc.contributor.authorMocan, Andrei
dc.contributor.authorAktümsek, Abdurrahman
dc.date.accessioned2020-03-26T19:24:56Z
dc.date.available2020-03-26T19:24:56Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesi, Fen Fakültesi, Biyoloji Bölümüen_US
dc.description.abstractDifferent wild plants commonly used in folk medicine, such as different species from the genus Lathyrus, may represent new sources of biologically active compounds. Hence, a study of the composition and (bio)chemical behaviour of extracts from these plants may provide valuable information. To evaluate the phytochemical profile, and the enzyme inhibition and antioxidant activities of the aerial parts of L. pratensis and L. aureus, extracts from both plants were analyzed by high-performance liquid chromatography with electrospray ionization mass spectrometric detection (HPLC-ESI-MSn). The in vitro antioxidant activity (phosphomolybdenum, beta-carotene bleaching, DPPH, ABTS, FRAP, CUPRAC and metal chelating) and enzyme inhibitory activity (acetyl cholinesterase, butyrylcholinesterase, tyrosinase, alpha-amylase and alpha-glucosidase) were also investigated for these Lathyrus species. Flavonoids and saponins were the main groups of compounds detected in the extracts from both plants. Generally, the methanol and water extracts presented remarkable antioxidant and enzyme inhibitory effects; all the observed results are critically discussed. The content of organic compounds and the antioxidant and enzyme assays suggest that these plants may be further used in phytopharmaceutical or food industry applications.en_US
dc.description.sponsorshipUCLM Research Plan; Scientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [113Z892]en_US
dc.description.sponsorshipE. J. Llorent-Martinez acknowledges the financial support from the UCLM Research Plan. CICT from University of Jaen is also acknowledged. This research was also supported by The Scientific and Technological Research Council of Turkey (TUBITAK) (Project Number: 113Z892).en_US
dc.identifier.citationLlorent-Martinez, E. J., Ortega-Barrales, P., Zengin, G., Uysal, Ş., Ceylan, R., Güler, G. O., Mocan, A., Aktümsek, A. (2016). Lathyrus Aureus and Lathyrus Pratensis: Characterization of phytochemical profiles by liquid chromatography-mass spectrometry, and evaluation of their enzyme inhibitory and antioxidant activities. RSC Advances, 6, (92), 88996-89006. doi: https://www.doi.org/10.1039/c6ra17170b
dc.identifier.doi10.1039/c6ra17170ben_US
dc.identifier.endpage89006en_US
dc.identifier.issn2046-2069en_US
dc.identifier.issue92en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage88996en_US
dc.identifier.urihttps://dx.doi.org/10.1039/c6ra17170b
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33755
dc.identifier.volume6en_US
dc.identifier.wosWOS:000384441200011en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorZengin, Gökhan
dc.institutionauthorCeylan, Ramazan
dc.institutionauthorAktümsek, Abdurrahman
dc.language.isoenen_US
dc.publisherRoyal Society of Chemistryen_US
dc.relation.ispartofRSC Advancesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleLathyrus Aureus and Lathyrus Pratensis: Characterization of Phytochemical Profiles by Liquid Chromatography-Mass Spectrometry, and Evaluation of Their Enzyme Inhibitory and Antioxidant Activitiesen_US
dc.typeArticleen_US

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