A Rapid and High-Yielding Synthesis of Thiazoles and Aminothiazoles Using Tetrabutylammonium Salts

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Küçük Resim

Tarih

2010

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Pergamon-Elsevier Science Ltd

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

A convenient method for the synthesis of thiazoles and aminothiazoles by treatment of phenacyl bromides with thioamides/thiourea in the presence of tetra butylammonium hexafluorophosphate (Bu4NPF6) at room temperature was developed. The products having high yields were formed rapidly (within 15 min). The method is simple, rapid and practical, generating thiazole derivatives in excellent isolated yields. The structures of the newly synthesized products were identified by FT-IR, H-1 NMR, C-13 NMR spectroscopy and elemental analysis data.

Açıklama

Anahtar Kelimeler

Kaynak

Heterocycles

WoS Q Değeri

Q3

Scopus Q Değeri

Q4

Cilt

81

Sayı

12

Künye

Kocabaş, E., Sarıgüney, A. B., Coşkun, A., (2010). A Rapid and High-Yielding Synthesis of Thiazoles and Aminothiazoles Using Tetrabutylammonium Salts. Heterocycles, 81(12), 2849-2854. Doi: 10.3987/COM-10-12067