A Rapid and High-Yielding Synthesis of Thiazoles and Aminothiazoles Using Tetrabutylammonium Salts
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Date
2010
Journal Title
Journal ISSN
Volume Title
Publisher
Pergamon-Elsevier Science Ltd
Access Rights
info:eu-repo/semantics/openAccess
Abstract
A convenient method for the synthesis of thiazoles and aminothiazoles by treatment of phenacyl bromides with thioamides/thiourea in the presence of tetra butylammonium hexafluorophosphate (Bu4NPF6) at room temperature was developed. The products having high yields were formed rapidly (within 15 min). The method is simple, rapid and practical, generating thiazole derivatives in excellent isolated yields. The structures of the newly synthesized products were identified by FT-IR, H-1 NMR, C-13 NMR spectroscopy and elemental analysis data.
Description
Keywords
Journal or Series
Heterocycles
WoS Q Value
Q3
Scopus Q Value
Q4
Volume
81
Issue
12
Citation
Kocabaş, E., Sarıgüney, A. B., Coşkun, A., (2010). A Rapid and High-Yielding Synthesis of Thiazoles and Aminothiazoles Using Tetrabutylammonium Salts. Heterocycles, 81(12), 2849-2854. Doi: 10.3987/COM-10-12067
