Behaviours of drugs in the milk - A review

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dc.contributor.authorOzdemir, Zeynep
dc.contributor.authorTraş, Bünyamin
dc.date.accessioned2020-03-26T20:11:44Z
dc.date.available2020-03-26T20:11:44Z
dc.date.issued2018
dc.departmentSelçuk Üniversitesi, Veteriner Fakültesi, Klinik Öncesi Bilimler Bölümüen_US
dc.description.abstractMilk is a food containing many biologically active substances that have an important place in the nourishment of newborns and adults. The transition of the drugs used in the treatment, as well as the environmental pollutants to milk cause a potential risk for consumer health as well as economical losses due to exceed of the legal limits of these compounds set by authorities. The transition of these chemicals to milk is complex; while active transport and passive diffusion play were found to have an important role. The transition abilities of the drugs into milk are defined by milk/plasma ratio. The M/P ratios of the drugs are affected by the composition of the milk and the physicochemical properties of the drug. The concentration of the drugs in the milk depends on the factors of the drug (protein binding, ionization, molecular weight, lipophilicity, drug-drug and drug-nutrient interactions) and organism (race, species, lactation period, parity, disease and nutrition). If the transition properties of the compounds of concern are known or able to be modelized in kinetic applications, it can be useful for preventing milk from drug residues.The success of mastitis treatment depends on the proper use of drugs and knowing of the behaviour of drugs in the milk. © Ataturk Universitesi. All rights reserved.en_US
dc.identifier.citationÖzdemir, Z., Traş, B. (2018). Behaviours of Drugs in the Milk - A Review. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, 13(3), 364-372.
dc.identifier.doi10.17094/ataunivbd.319443en_US
dc.identifier.endpage372en_US
dc.identifier.issn1306-6137en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage364en_US
dc.identifier.urihttps://dx.doi.org/10.17094/ataunivbd.319443
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37177
dc.identifier.volume13en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorTraş, Bünyamin
dc.language.isoenen_US
dc.publisherAtaturk Universitesien_US
dc.relation.ispartofAtaturk Universitesi Veteriner Bilimleri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectBehaviouren_US
dc.subjectDrugen_US
dc.subjectFactoren_US
dc.subjectDavranışen_US
dc.subjectFaktören_US
dc.subjectGeçiş
dc.titleBehaviours of drugs in the milk - A reviewen_US
dc.title.alternativeİlaçların sütteki davranışları - derlemeen_US
dc.typeArticleen_US

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