Effects of fluoroquinolone antibiotics on hepatic superoxide dismutase and glutathione peroxidase activities in healthy and experimentally induced peritonitis mice

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dc.contributor.authorYazar, E
dc.contributor.authorTras, B
dc.date.accessioned2020-03-26T16:37:06Z
dc.date.available2020-03-26T16:37:06Z
dc.date.issued2001
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIn this study, effects of fluoroquinolone antibiotics were investigated on hepatic superoxide dismutase and glutathione peroxidase activities in healthy and experimentally induced peritonitis mice. One hundred thirty two mice randomly divided into six groups. Group 1 served as control, group 2 was injected enrofloxacin, group 3 was injected danofloxacin, group 4 was injected E. coli, and group 5 and group 6 were injected enrofloxacin and danofloxacin, respectively, after the injection E. roll. Hepatic superoxide dismutase and glutathione peroxidase activities were measured by spectrophotometer. As results, enrofloxacin caused a decrease glutathione peroxidase activity at 24, 48 and 72 hours, and danofloxacin caused an increase superoxide dismutase activity at 24 and 48 hours after the injection. Danofloxacin and E. coli caused a decrease glutathione peroxidase activity during all experimental period after the injection.en_US
dc.identifier.endpage238en_US
dc.identifier.issn0035-1555en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage235en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17537
dc.identifier.volume152en_US
dc.identifier.wosWOS:000168722400002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherECOLE NATIONALE VETERINAIRE TOULOUSEen_US
dc.relation.ispartofREVUE DE MEDECINE VETERINAIREen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectenrofloxacinen_US
dc.subjectdanofloxacinen_US
dc.subjectE. colien_US
dc.subjectsuperoxide dismutaseen_US
dc.subjectglutathione peroxidaseen_US
dc.titleEffects of fluoroquinolone antibiotics on hepatic superoxide dismutase and glutathione peroxidase activities in healthy and experimentally induced peritonitis miceen_US
dc.typeArticleen_US

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