Evaluation of Biocompability of Supramolecular Calixarene on L-929 by Real Time Cell Analysis

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dc.contributor.authorArpaci, P. Uyar
dc.contributor.authorOzcan, F.
dc.contributor.authorOmar, N.
dc.contributor.authorErtul, S.
dc.date.accessioned2020-03-26T19:41:43Z
dc.date.available2020-03-26T19:41:43Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description7th IEEE International Conference Nanomaterials - Application and Properties (NAP) -- SEP 10-15, 2017 -- Odessa, UKRAINEen_US
dc.description.abstractThe cytotoxicity test is one of the biological evaluation and screening tests that use tissue cells in vitro to observe the cell growth, reproduction and morphological effects by medical devices. Cytotoxicity is preferred as a pilot project test and an important indicator for toxicity evaluation of medical devices as it is simple, fast, has a high sensitivity and can save animals from toxicity. Three types of cytotoxicity test are stated in the International Organization for Standardization 109993-5: Extract, direct contact and indirect contact tests. The xCELLigence real- time cell analysis system shows a significant potential in regards to cytotoxicity in recent years. The proliferation of L-929 were observed in the Real-Time Cell Analysis (RTCA) Systems. Our research directs that calixarene shows no cytotoxicity at a concentration range of 25 to 100 mu g/mL on L929 cells. There were no significant differences between the L929 cell indexes of the control and all testing groups at 24, 48 and 72 h.en_US
dc.description.sponsorshipIEEE, Minist Educ Sci Ukraineen_US
dc.identifier.isbn978-1-5386-2810-2
dc.identifier.issn2306-580Xen_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/35091
dc.identifier.wosWOS:000426973100164en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherIEEEen_US
dc.relation.ispartofPROCEEDINGS OF THE 2017 IEEE 7TH INTERNATIONAL CONFERENCE NANOMATERIALS: APPLICATION & PROPERTIES (NAP)en_US
dc.relation.ispartofseriesProceedings of the international conference Nanomaterials-Applications and properties
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectcytotoxicityen_US
dc.subjectbiocompatibilityen_US
dc.subjectxCELLigenceen_US
dc.subjectcalixareneen_US
dc.titleEvaluation of Biocompability of Supramolecular Calixarene on L-929 by Real Time Cell Analysisen_US
dc.typeConference Objecten_US

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