Febril nötropenik atakların değerlendirilmesi
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Dosyalar
Tarih
2002
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışmada, ateşli nötrbpenik olgularda infeksiyon odakları, uygulanan tedavi rejimleri, tedavide başarı oranı ve mortalite oranı araştırıldı. Çalışmamızda, toplam 67 hastada gözlenen 82 ateşli nötropenik atak değerlendirildi. Olguların 41'i lösemi, 9'u lenfoma, 8'i diğer hematolojik malignitelere sahipti ve 9'unda herhangi bir hematolojik malignité bulunmuyordu. Olgularda yapılan incelemeler sonucunda, 35 (%42.7) hastada mikrobiyolojik olarak dokümante edilen infeksiyon, 30 (%36.6) hastada klinik olarak tespit edilmiş infeksiyon, 17 (%20.7) hastada nedeni saptanamayan ateş tespit edildi. Total nötrofil sayısı ile ateş nedenleri arasında anlamlı bir fark görülmedi (p 0.05). Olguların %75.6'sına kombine tedavi, %14.6'sına monoterapi, %9.8'ine değişik tedaviler verilmiştir. Olguların 61 (%88.4)'inde tedavide başarı elde edilmiş, 8 (%l l.6)"ı kaybedilmiştir.
In this study, origin of infection, therapeutic protocols, success and mortality rate of therapy were investigated in febrile neutropenic cases. Eighty-two febrile neutropenic attacks in 67 patients (42 male, 25 female) between age 2-82 years were evaluated in this study. Forty-one of the patients were diagnosed as leukemia, 9 as lymphoma, 8 as other hematological malignancies. No hematological malignancies were found at 9 patients. At the end of the examinations, microbiologically documented infection was reported in 35 (42.7%) patients, clinically defined infection was reported in 30 (36.6%), and fever of unknown origin was reported in 17 (20.7%) patients. There was no statistically significant difference between absolute neutrophil count and aetiology of fever (p> 0.05). 75.6% of patients were treated with combined therapy, 14.6% of patients with monotherapy and 9.8% of them were treated with different therapies. Success in treatment was achieved at 61 (88.4%) patients, 8 (I 1.6%) patients died.
In this study, origin of infection, therapeutic protocols, success and mortality rate of therapy were investigated in febrile neutropenic cases. Eighty-two febrile neutropenic attacks in 67 patients (42 male, 25 female) between age 2-82 years were evaluated in this study. Forty-one of the patients were diagnosed as leukemia, 9 as lymphoma, 8 as other hematological malignancies. No hematological malignancies were found at 9 patients. At the end of the examinations, microbiologically documented infection was reported in 35 (42.7%) patients, clinically defined infection was reported in 30 (36.6%), and fever of unknown origin was reported in 17 (20.7%) patients. There was no statistically significant difference between absolute neutrophil count and aetiology of fever (p> 0.05). 75.6% of patients were treated with combined therapy, 14.6% of patients with monotherapy and 9.8% of them were treated with different therapies. Success in treatment was achieved at 61 (88.4%) patients, 8 (I 1.6%) patients died.
Açıklama
Anahtar Kelimeler
Febril nötropeni, infeksiyon, Tedavi, Febrile neutropenia, Infection, Treatment
Kaynak
Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
7
Sayı
3
Künye
Dikici, N., Ural, O. (2002). Febril Nötropenik Atakların Değerlendirilmesi. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, 7(3), 185-190.
