Effects of Cooling on Contractions of Calf Coronary Artery: Role of the Endothelium

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dc.contributor.authorAtalık, Kısmet Esra
dc.contributor.authorŞahin, A. S.
dc.contributor.authorDoğan, N.
dc.date.accessioned2020-03-26T16:37:40Z
dc.date.available2020-03-26T16:37:40Z
dc.date.issued2001
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe effects of cooling on vasoconstrictions induced by contractile agents and role of the endothelium in this effect were analyzed in calf coronary artery. Potassium chloride (KCl, 10-3 - 5 × 102 M), 5-hydroxytryptamine (5-HT, 10-9 - 3 × 10-4 M) and carbachol (10-9 - 3 × 10-4 M) induced concentration-dependent contractions at both 37°C and 28°C (cooling). During cooling the sensitivities, but not the maximal responses to KCl, 5-HT and carbachol were significantly lower than at 37°C. Endothelium removal or NG-nitro-L arginine methyl esther (LNAME, 10-5 M) pretreatment did not modify the effect of cooling. These results suggest that cooling-induced responses in calf coronary artery are independent of endothelium (nitric oxide).en_US
dc.identifier.citationAtalık, K. E., Şahin, A. S., Doğan, N., (2001). Effects of Cooling on Contractions of Calf Coronary Artery: Role of the Endothelium. Asia Pacific Journal of Pharmacology, 15(3), 33-36.
dc.identifier.endpage36en_US
dc.identifier.issn0217-9687en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage33en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/17675
dc.identifier.volume15en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorAtalık, Kısmet Esra
dc.institutionauthorŞahin, A. S.
dc.institutionauthorDoğan, N.
dc.language.isoenen_US
dc.relation.ispartofAsia Pacific Journal of Pharmacologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectContractionsen_US
dc.subjectCoolingen_US
dc.subjectCoronary artery (calf)en_US
dc.subjectNitric oxideen_US
dc.titleEffects of Cooling on Contractions of Calf Coronary Artery: Role of the Endotheliumen_US
dc.typeArticleen_US

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