Influence of cumulus cell coculture and cumulus-aided embryo transfer on embryonic development and pregnancy rates

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dc.contributor.authorCihangir, Nalan
dc.contributor.authorGörkemli, Hüseyin
dc.contributor.authorÖzdemir, Suna
dc.contributor.authorAktan, Murad
dc.contributor.authorDuman, Selçuk
dc.date.accessioned2020-03-26T18:05:43Z
dc.date.available2020-03-26T18:05:43Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: In this study, we aimed to evaluate the influence of autologous cumulus oocyte complex (COC) coculture on embryonic development and quality, and investigate the implantation and pregnancy rates after cumulus-aided embryo transfer in the ICSI-ET cycles. Material and Methods: Ninety five consecutive infertile women undergoing their first cycle of IVF teratment were included in the study. The cases were divided into two groups. Group 1 consisted of 48 women undergoing ICSI, along with autologous cumulus embryo coculture and cumulus-aided emryo transfer. Group 2 comprised 47 consecutive patients who consented to undergo ICSI and in whom autologous cumulus embryo coculture and cumulus-aided embryo transfer were not performed. Implantation and pregnancy rates were compared between the two groups. Results: The demographic data and controlled ovarian hyperstimulation parameters were similar in the two groups. The fertilization and cleavage rates were found to be higher in group 1 when compared with group 2 (p=0.03 and 0.001, respectively). There were no statistical significant differences for the implantation and clinical pregnancy rates between the two groups. Conclusion: Usage of autologous COCs as coculture may improve fertilization and cleavage rates. However, cumulus-aided embryo transfer does not produce an increase in implantation and pregnancy rates.en_US
dc.identifier.doi10.5152/jtgga.2010.017en_US
dc.identifier.endpage126en_US
dc.identifier.issn1309-0399en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage121en_US
dc.identifier.urihttps://dx.doi.org/10.5152/jtgga.2010.017
dc.identifier.urihttps://hdl.handle.net/20.500.12395/25513
dc.identifier.volume11en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isotren_US
dc.publisherAVESen_US
dc.relation.ispartofJournal of the Turkish German Gynecology Associationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCocultureen_US
dc.subjectCumulus cellsen_US
dc.subjectIcsi-embryo transferen_US
dc.subjectPregnancy rateen_US
dc.titleInfluence of cumulus cell coculture and cumulus-aided embryo transfer on embryonic development and pregnancy ratesen_US
dc.title.alternativeKumulus hücre kokültürünün ve kumulus destekli embryo transferinin embryonic gelişim ve gebelik oranlarına etkisi
dc.typeArticleen_US

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