Chemical Profile, Antioxidant Properties and Enzyme Inhibitory Effects of the Root Extracts of Selected Potentilla Species

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dc.authorid0000-0002-5151-2650
dc.authorid0000-0002-8901-6484
dc.contributor.authorUysal, Şengül
dc.contributor.authorZengin, Gökhan
dc.contributor.authorMahomoodally, Mohamad Fawzi
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.contributor.authorAktümsek, Abdurrahman
dc.date.accessioned2020-03-26T20:12:54Z
dc.date.available2020-03-26T20:12:54Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Fen Fakültesi, Biyoloji Bölümüen_US
dc.description.abstractPlants from the genus Potentilla have been traditionally used for therapeutic purposes in Turkey. Methanol root extracts from four selected Potentilla species (P. anatolica, P. argentea, P. recta, and P. reptans) were probed for their chemical composition, antioxidant properties (DPPH, ABTS, FRAP, CUPRAC, phosphomolybdenum, and metal chelating activity), and enzyme (acetylcholinesterase (AChE), butyrylcholinesterase (BChE), alpha-amylase, alpha-glucosidase, and tyrosinase) inhibition effects. In addition, the total phenolic, flavonoid, saponin, and triterpenoid content of the extracts were determined. Ultra-high performance liquid chromatography (UHPLC)-electrospray ionization (ESI)-tandemmass spectrometry (MS/MS) analysis revealed that the main phenolic components in extracts were coumarin, hesperidin, p-coumaric acid, gallic acid, and rutin. P. recta and P. reptans showed the highest total phenolic, saponin, and triterpenoid content. The root extracts showed significant antioxidant properties and depicted significant inhibitory effects against AChE, BChE, alpha-amylase, alpha-glucosidase, and tyrosinase. In conclusion, root extracts of Potentilla may be considered as new natural antioxidants and key enzyme inhibitors that can be exploited as bioproducts for pharmaceutical industries. (c) 2018 SAAB. Published by Elsevier B.V. All rights reserved.en_US
dc.identifier.citationUysal, Ş., Zengin, G., Mahomoodally, M. F., Yılmaz, M. A., Aktümsek, A. (2019). Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species. South African Journal of Botany, 120, 124-128. doi: https://dx.doi.org/10.1016/j.sajb.2018.01.014
dc.identifier.doi10.1016/j.sajb.2018.01.014en_US
dc.identifier.endpage128en_US
dc.identifier.issn0254-6299en_US
dc.identifier.issn1727-9321en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage124en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.sajb.2018.01.014
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37575
dc.identifier.volume120en_US
dc.identifier.wosWOS:000456314600014en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorZengin, Gökhan
dc.institutionauthorAktümsek, Abdurrahman
dc.language.isoenen_US
dc.publisherELSEVIERen_US
dc.relation.ispartofSouth African Journal of Botanyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectPotentillaen_US
dc.subjectNatural productsen_US
dc.subjectPhenolicsen_US
dc.subjectBiaoctive agentsen_US
dc.subjectDoğal ürünler
dc.subjectFenolikler
dc.subjectBiyoaktif ajanlar
dc.titleChemical Profile, Antioxidant Properties and Enzyme Inhibitory Effects of the Root Extracts of Selected Potentilla Speciesen_US
dc.typeArticleen_US

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