Clinical Comparison of Medetomidine with Isoflurane or Sevoflurane for Anesthesia in Horses

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dc.contributor.authorArican, Mustafa
dc.contributor.authorErol, Hanifi
dc.contributor.authorEsin, Evren
dc.date.accessioned2020-03-26T19:01:23Z
dc.date.available2020-03-26T19:01:23Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe effects of anesthesia using medetomidine combined with isoflurane or sevoflurane on hemodynamic parameters, blood biochemistry, and intraocular pressure was evaluated in horses. Healthy horses (n=12) with a mean body weight of 438 +/- 51kg were used. Premedication was provided by administering medetomidine (7 mu g/kg) intravenously (IV), and general anesthesia was induced by administering ketamine (2.2 mg/kg) and midazolam (0.03 mg/kg) IV after which isoflurane (n=6) or sevoflurane (n=6) was administered for inhalation anesthesia. Blood gases, respiratory rate, heart rate, electrocardiogram, body temperature, and oxygen saturation, as well as systolic, diastolic, and mean arterial blood pressure were recorded at 0, 5, 15, 30, and 60 min after administering medetomidine. Statistically non-significant differences in the study variables were observed between the isoflurane and sevoflurane groups. Blood gases and electrolyte parameters in both groups were unchanged. Intraocular pressure and liver enzymes levels were similar to reference values. Anesthesia protocols of study using medetomidine combined with isoflurane or sevoflurane produced minimal complications in horses. Medetomidine with sevoflurane provided deep anesthesia, and had fewer cardiopulmonary effects than medetomidine with isoflurane. (C) 2015 PVJ. All rights reserveden_US
dc.description.sponsorshipUniversity of Selcuk (Scientific Research Projects (BAP))Selcuk University [08401072]en_US
dc.description.sponsorshipThe authors would like to thank of Prof. Dr. Ayse Topal for her help for the study. We would like also to thank for financial support by University of Selcuk (Scientific Research Projects (BAP) (Project No. 08401072).en_US
dc.identifier.endpage478en_US
dc.identifier.issn0253-8318en_US
dc.identifier.issn2074-7764en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage474en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/31934
dc.identifier.volume35en_US
dc.identifier.wosWOS:000366758200016en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherUNIV AGRICULTURE, FAC VETERINARY SCIENCEen_US
dc.relation.ispartofPAKISTAN VETERINARY JOURNALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectHorseen_US
dc.subjectIsofluraneen_US
dc.subjectMedetomidineen_US
dc.subjectSevofluraneen_US
dc.titleClinical Comparison of Medetomidine with Isoflurane or Sevoflurane for Anesthesia in Horsesen_US
dc.typeArticleen_US

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