SERUM LEVELS OF CALCIUM, SELENIUM, MAGNESIUM, PHOSPHORUS, CHROMIUM, COPPER AND IRON THEIR RELATION TO ZINC IN RATS WITH INDUCED HYPOTHYROIDISM

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dc.contributor.authorBaltaci, Abdulkerim Kasim
dc.contributor.authorMogulkoc, Rasim
dc.contributor.authorBelviranli, Muaz
dc.date.accessioned2020-03-26T18:43:19Z
dc.date.available2020-03-26T18:43:19Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThere is an important relation between thyroid hormones and zinc. Establishment of low zinc levels in hypothyroidism and high levels in hyperthyroidism is a significant proof of this relation. The aim of the present study was to explore changes in serum levels of some elements and their relation to zinc in rats with hypothyroidism. Thirty adult male rats of Sprague-Dawley type were divided into 3 equal groups: group 1, control; group 2, sham-hypothyroidism group supplemented with 10 mg/kg serum physiologic i.p. for 4 weeks; and group 3, hypothyroidism group supplemented with 10 mg/kg propylthiouracil i.p. for 4 weeks. Blood samples were collected from all animals by decapitation and serum calcium, phosphorus, chromium, copper, iron, magnesium, selenium and zinc levels were analyzed using an atomic emission apparatus. Group 3 had lower calcium, selenium and zinc levels, and higher chromium, copper, iron and phosphorus levels (p<0.01 all) relative to groups 1 and 2. Study parameters did not differ between groups 1 and 2. Results obtained in this study indicate that hypothyroidism leads to changes in serum levels of some elements in rats. These changes may be associated with reduced zinc levels in hypothyroidism.en_US
dc.identifier.endpage156en_US
dc.identifier.issn0353-9466en_US
dc.identifier.issue2en_US
dc.identifier.pmid24053074en_US
dc.identifier.startpage151en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29808
dc.identifier.volume52en_US
dc.identifier.wosWOS:000324355700002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSESTRE MILOSRDNICE UNIV HOSPITALen_US
dc.relation.ispartofACTA CLINICA CROATICAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectSeleniumen_US
dc.subjectCopperen_US
dc.subjectZincen_US
dc.subjectIronen_US
dc.subjectHypothyroidismen_US
dc.subjectRaten_US
dc.titleSERUM LEVELS OF CALCIUM, SELENIUM, MAGNESIUM, PHOSPHORUS, CHROMIUM, COPPER AND IRON THEIR RELATION TO ZINC IN RATS WITH INDUCED HYPOTHYROIDISMen_US
dc.typeArticleen_US

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