Antibacterial, cytotoxicity, and phytotoxicity profiles of three medicinal plants collected from Pakistan

Yükleniyor...
Küçük Resim

Tarih

2017

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

MARMARA UNIV, FAC PHARMACY

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

The purpose of present research was to examine the antibacterial, cytotoxic, and phytotoxic profiles of three important Pakistani medicinal plants viz., Teucrium stocksianum, Chenopodium botrys, and Micromeria biflora. The antibacterial, cytotoxicity, and phytotoxicity activities of samples extracted from these plants were evaluated by a modified agar well-diffusion method, brine shrimps cytotoxic assay, and Lemna acquinoctialis-based phytotoxic assay, respectively. Results revealed marked susceptibility of both the crude extracts and the aqueous fractions of these plants against K. pneumonia and B. subtilis. Methanolic extracts and aqueous fractions exhibited significant cytotoxicity in a concentration-dependent manner. Similarly, an outstanding phytotoxic effect was observed for the extracts/fractions. Accordingly, the extracts and fractions of the aforementioned plants possess potential antibacterial, cytotoxic, and phytotoxic effects which could be useful in the search and development of new pharmaceutical agents.

Açıklama

Anahtar Kelimeler

Teucrium stocksianum, Chenopodium botrys, Micromeria biflora, antibacterial activity, cytotoxicity, phytotoxicity

Kaynak

Marmara Pharmaceutical Journal

WoS Q Değeri

N/A

Scopus Q Değeri

Cilt

21

Sayı

2

Künye

Rauf, A., Uysal, S., Hadda, T. B., Siddiqui, B. S., Khan, H., Khan, M. A., Ijaz, M., Mubarak, M. S., Bawazeer, S., Izneid, T. A., Khan, A., Farooq, U. (2017). Antibacterial, Cytotoxicity, and Phytotoxicity Profiles of Three Medicinal Plants Collected from Pakistan. Marmara Pharmaceutical Journal, 21(2), 261-268.