Antibacterial, cytotoxicity, and phytotoxicity profiles of three medicinal plants collected from Pakistan
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Date
2017
Journal Title
Journal ISSN
Volume Title
Publisher
MARMARA UNIV, FAC PHARMACY
Access Rights
info:eu-repo/semantics/openAccess
Abstract
The purpose of present research was to examine the antibacterial, cytotoxic, and phytotoxic profiles of three important Pakistani medicinal plants viz., Teucrium stocksianum, Chenopodium botrys, and Micromeria biflora. The antibacterial, cytotoxicity, and phytotoxicity activities of samples extracted from these plants were evaluated by a modified agar well-diffusion method, brine shrimps cytotoxic assay, and Lemna acquinoctialis-based phytotoxic assay, respectively. Results revealed marked susceptibility of both the crude extracts and the aqueous fractions of these plants against K. pneumonia and B. subtilis. Methanolic extracts and aqueous fractions exhibited significant cytotoxicity in a concentration-dependent manner. Similarly, an outstanding phytotoxic effect was observed for the extracts/fractions. Accordingly, the extracts and fractions of the aforementioned plants possess potential antibacterial, cytotoxic, and phytotoxic effects which could be useful in the search and development of new pharmaceutical agents.
Description
Keywords
Teucrium stocksianum, Chenopodium botrys, Micromeria biflora, antibacterial activity, cytotoxicity, phytotoxicity
Journal or Series
Marmara Pharmaceutical Journal
WoS Q Value
N/A
Scopus Q Value
Volume
21
Issue
2
Citation
Rauf, A., Uysal, S., Hadda, T. B., Siddiqui, B. S., Khan, H., Khan, M. A., Ijaz, M., Mubarak, M. S., Bawazeer, S., Izneid, T. A., Khan, A., Farooq, U. (2017). Antibacterial, Cytotoxicity, and Phytotoxicity Profiles of Three Medicinal Plants Collected from Pakistan. Marmara Pharmaceutical Journal, 21(2), 261-268.
