Koyunlarda Tarantula cubensis alkolik ekstraktının (Theranekron®) serum tiyobarbitürik asit reaktif ürünlerine etkisi
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Dosyalar
Tarih
2014
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Selçuk Üniversitesi Veterinerlik Fakültesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Mevcut araştırmanın amacı koyunlarda Tarantula cubensis alkolik ekstraktının serum tiyobarbitürik asit reaktif ürünlerine etkisini değerlendirmektir. Ayrıca hematolojik ve biyokimyasal parametrelere etkilerini değerlendirmektir. Gereç ve Yöntem: Altı adet Akkaraman koyuna tek doz (6 mL/koyun, SC) Tarantula cubensis alkolik ekstraktı uygulandı. Kan örnekleri uygulamadan hemen önce (0 saat, kontrol) ve sonraki 2, 4, 8, 12, 24 ve 48. saatlerde alındı. Serum tiyobarbitürik asit reaktif ürünleri düzeyi ELISA okuyucusunda belirlendi. Biyokimyasal ve hematolojik parametreler sırası ile otoanalizör ve kan hücresi sayım cihazında belirlendi. Bulgular: Tarantula cubensis alkolik ekstraktı koyunlarda serum tiyobarbitürik asit reaktif ürünleri düzeyini belirgin şekilde düşürdü, ancak istatistiki fark belirlenmedi. Ayrıca ekstratın hematolojik ve biyokimyasal parametrelere olumsuz etkisi belirlenmedi. Öneri: Tarantula cubensis alkolik ekstraktının antioksidan etkinlik gösterebileceği ve kısa süreli değerlendirilmesi dikkate alındığında koyunlarda güvenli olabileceği ifade edilebilir.
Aim: The aim of the current research was to evaluate the effect of alcoholic extract of Tarantula cubensis on serum thiobarbituric acid-reactive species concentrations in sheep. Furthermore, it’s effect on the hematological and biochemical values were determined. Materials and Methods: Six Akkaraman sheep were administered single dose (6 mL/sheep, SC) of alcoholic extract of Tarantula cubensis. Blood samples were obtained before (0 hour, control) and 2, 4, 8, 12, 24 and 48 hours after administration. Serum thiobarbituric acid-reactive species concentrations were measured by ELISA reader. The concentrations of biochemical and hemogram values were measured by autoanalyzer and blood cell counter, respectively. Results: Alcoholic extract of Tarantula cubensis dramatically decreased on serum thiobarbituric acid-reactive species concentrations in sheep but no statistically significant. In addition, it had no any negative effect on the hematological and biochemical values. Conclusions: It is stated that alcoholic extract of Tarantula cubensis may cause antioxidant effect and it may be accepted safe in sheep when evaluation of short time duration was considered.
Aim: The aim of the current research was to evaluate the effect of alcoholic extract of Tarantula cubensis on serum thiobarbituric acid-reactive species concentrations in sheep. Furthermore, it’s effect on the hematological and biochemical values were determined. Materials and Methods: Six Akkaraman sheep were administered single dose (6 mL/sheep, SC) of alcoholic extract of Tarantula cubensis. Blood samples were obtained before (0 hour, control) and 2, 4, 8, 12, 24 and 48 hours after administration. Serum thiobarbituric acid-reactive species concentrations were measured by ELISA reader. The concentrations of biochemical and hemogram values were measured by autoanalyzer and blood cell counter, respectively. Results: Alcoholic extract of Tarantula cubensis dramatically decreased on serum thiobarbituric acid-reactive species concentrations in sheep but no statistically significant. In addition, it had no any negative effect on the hematological and biochemical values. Conclusions: It is stated that alcoholic extract of Tarantula cubensis may cause antioxidant effect and it may be accepted safe in sheep when evaluation of short time duration was considered.
Açıklama
Anahtar Kelimeler
Tarantula cubensis, tiyobarbitürik asit reaktif ürünleri, güvenlik, koyun, thiobarbituric acid-reactive species, safety, sheep
Kaynak
Eurasian Journal of Veterinary Sciences
WoS Q Değeri
Scopus Q Değeri
Cilt
30
Sayı
2
Künye
Dik, B., Er, A., Çorum, O., (2014). Koyunlarda Tarantula cubensis alkolik ekstraktının (Theranekron®) serum tiyobarbitürik asit reaktif ürünlerine etkisi. Eurasian Journal of Veterinary Sciences, 30 (2), 68-71. DOI:10.15312/EurasianJVetSci.201425921
