Systemic inflammatory response markers in preeclampsia

Basit Öğe Kaydı
dc.contributor.authorÇintesun, Ersin
dc.contributor.authorÇintesun, Feyza Nur İncesu
dc.contributor.authorEzveci, Hüriye
dc.contributor.authorAkyürek, Fikret
dc.contributor.authorÇelik, Çetin
dc.date.accessioned2020-03-26T19:55:52Z
dc.date.available2020-03-26T19:55:52Z
dc.date.issued2018
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPURPOSE: Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), platelet distribution width (PDW), red cell distribution width (RDW), mean platelet volume (MPV), and plateletcrit (PCT) are known as systemic inflammatory response markers. In this study, we aimed to evaluate changes in NLR, PLR, PDW, RDW, MPV, and PCT in preeclampsia (PE) and their use in predicting its severity. MATERIALS AND METHODS: This is a retrospective case-control study. The study comprised 64 control group (healthy pregnant females), 51 females with mild PE, and 13 with severe PE. These three groups were compared with demographic data and inflammation markers. RESULTS: There were no statistically significant differences between healthy pregnant females and preeclaptic females in terms of median age, hemoglobin, lymphocyte, neutrophil, platelet, NLR, PLR, PDV, RDW, MPV, PCT (P > 0.05). The control group has a higher number of gravity and parity than the PE group (P < 0.001). MPV value is a lower PE group than the control group (P < 0.001). Both gravity and parity were significantly higher in the patients with mild PE than in the control group (P < 0.001). MPV value was statistically higher in the control group compared both mild and severe PE (P < 0.001), however, no statistical difference between mild and severe PE (P = 0.305). CONCLUSIONS: MPV may be clinically useful markers in the prediction of PE. Further, prospective multicenter studies are needed to reveal the association between these markers and PE.en_US
dc.identifier.doi10.4103/JLP.JLP_144_17en_US
dc.identifier.endpage319en_US
dc.identifier.issn0974-2727en_US
dc.identifier.issn0974-7826en_US
dc.identifier.issue3en_US
dc.identifier.pmid30078969en_US
dc.identifier.startpage316en_US
dc.identifier.urihttps://dx.doi.org/10.4103/JLP.JLP_144_17
dc.identifier.urihttps://hdl.handle.net/20.500.12395/36977
dc.identifier.volume10en_US
dc.identifier.wosWOS:000438559300012en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWOLTERS KLUWER MEDKNOW PUBLICATIONSen_US
dc.relation.ispartofJOURNAL OF LABORATORY PHYSICIANSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectInflammatoryen_US
dc.subjectlymphocyteen_US
dc.subjectneutrophilen_US
dc.subjectplateleten_US
dc.subjectpreeclampsiaen_US
dc.titleSystemic inflammatory response markers in preeclampsiaen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu