Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis

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dc.contributor.authorAumeeruddy, Muhammad Zakariyyah
dc.contributor.authorAumeeruddy-Elalfi, Zaahira
dc.contributor.authorNeetoo, Hudaa
dc.contributor.authorZengin, Gökhan
dc.contributor.authorFibrich, Bianca
dc.contributor.authorRademan, Sunelle
dc.contributor.authorvan Staden, Analike Blom
dc.date.accessioned2020-03-26T19:52:59Z
dc.date.available2020-03-26T19:52:59Z
dc.date.issued2018
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThis study was designed to evaluate and correlate the biological, phytochemical, and physicochemical properties of two NSS (Nigella sativa seed) oils (N1 and N2). The biological activity was evaluated in terms of antibacterial, antioxidant (nitric oxide scavenging), antielastase, antityrosinase, antimelanogenic, and anticancer activity. Physicochemical properties including colour, total soluble solids (TSS), and density were also investigated. N2 exhibited higher antibacterial, NO scavenging, extracellular antimelanogenic, and anticancer activity against the HeLa cell line compared to N1, which showed higher antityrosinase activity. TPC (total phenolic content) and TFC (total flavonoid content) of N1 were significantly higher than N2 while TTC (total tannin content) was higher in N2. In fact, TTC was strongly correlated (R=1.000) with the antioxidant, extracellular antimelanogenic, and HeLa cell inhibitory activity. To conclude, NSS oil may be considered as a complementary and alternative therapy in the management of infectious and chronic diseases but warrants further in vivo pharmacological validation and toxicological analysis.en_US
dc.identifier.citationAumeeruddy, M. Z., Aumeeruddy-Elalfi Z., Neetoo H., Zengin G., Fibrich B., Rademan S., van Staden A. B. (2018). Biological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysis. ISTANBUL JOURNAL OF PHARMACY, 48(3), 89-99.
dc.identifier.doi10.26650/IstanbulJPharm.2018.180003en_US
dc.identifier.endpage99en_US
dc.identifier.issn0367-7524en_US
dc.identifier.issn2548-0731en_US
dc.identifier.issue3en_US
dc.identifier.pmid#YOKen_US
dc.identifier.startpage89en_US
dc.identifier.urihttps://dx.doi.org/10.26650/IstanbulJPharm.2018.180003
dc.identifier.urihttps://hdl.handle.net/20.500.12395/36367
dc.identifier.volume48en_US
dc.identifier.wosWOS:000456247200007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherISTANBUL UNIV, FAC PHARMACYen_US
dc.relation.ispartofISTANBUL JOURNAL OF PHARMACYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectNigella sativaen_US
dc.subjectbiologicalen_US
dc.subjectphytochemicalen_US
dc.subjectphysicochemicalen_US
dc.titleBiological, phytochemical, and physico-chemical properties of two commercial Nigella sativa seed oils: A comparative analysisen_US
dc.typeArticleen_US

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