The Association of Peritoneal Transport Properties With 24-hour Blood Pressure Levels in Capd Patients

Yükleniyor...
Küçük Resim

Tarih

2003

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Multimed Inc

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Objectives: We aimed to investigate the effects of peritoneal transport characteristics on blood pressure (BP) parameters, measured by 24-hour ambulatory blood pressure monitoring (ABPM), and on the development of left ventricular hypertrophy (LVH) in continuous ambulatory peritoneal dialysis (CAPD) patients. Design: Cross-sectional and prospective design. * Setting: Tertiary-care center. Patients: 25 CAPD patients (11 male, 14 female; mean age 47 +/- 14 years) were included. Mean time on CAPD was 22.9 +/- 18 months and all patients had been dialyzed for more than 6 months. The patients were divided into high, high-average, low-average, and low transport groups according to peritoneal equilibration test results. Main Outcome Measures: Daytime and nighttime systolic and diastolic BP and left ventricular mass index among the different peritoneal transport groups; changes in BP parameters before and after increase in ultrafiltration. Results: On 24-hour ABPM records, 13 patients (52%) were found to be hypertensive. Both mean systolic and diastolic BP were significantly increased in high-transporter groups compared to low transporters in both daytime and nighttime BP parameters. Left ventricular mass index was higher in high transporters compared to low transporters, without reaching statistical significance: 160 +/- 23 vs 119 +/- 41 g/m(2), p > 0.05. Following increase in ultrafiltration, mean systolic (145 +/- 13 vs 128 +/- 5 mmHg, p < 0.001) and diastolic (96 +/- 10 vs 81 +/- 3 mmHg, p < 0.001) BP decreased, and BP levels returned to normotensive levels in 6 (46%) of the 13 hypertensive patients, requiring discontinuation of anti hypertensive drugs. Conclusion: Improvement in volume status resulted in a decrease in both daytime and nighttime BR Differences in peritoneal transport properties were associated with the development of hypertension and LVH.

Açıklama

Anahtar Kelimeler

Hypertension, Left ventricular, Hypertrophy, Peritoneal transport, PET

Kaynak

Peritoneal Dialysis International

WoS Q Değeri

Q2

Scopus Q Değeri

Cilt

23

Sayı

1

Künye

Tonbul, Z., Altıntepe, L., Sözlü, Ç., Yeksan, M., Yıldız, A., Türk, S., (2003). The Association of Peritoneal Transport Properties With 24-hour Blood Pressure Levels in Capd Patients. Peritoneal Dialysis International, 23(1), 46-52.