The Protective Effect of Melatonin on Plasma Lipid Profile in Rats with Cerulein-İnduced Acute Pancreatitis

Basit Öğe Kaydı
dc.contributor.authorKeskin, Ercan
dc.contributor.authorUluışık, Deniz
dc.date.accessioned2023-09-01T17:35:48Z
dc.date.available2023-09-01T17:35:48Z
dc.date.issued2019 Eylülen_US
dc.departmentSelçuk Üniversitesi, Veteriner Fakültesi, Temel Bilimler Bölümüen_US
dc.description.abstractThe objective of this study was to assessment the effect of melatonin on lipid profile in rats with experimentally induced acute pancreatitis. In this study, 32 adult, male, healthy Wistar Abino rats were used. Group I animals was no applied. Group II animals was intraperitoneally administered 50 mg/kg melatonin per rat twice for two hours intervals. Animals of group III received two intraperitoneal injections of cerulein (50 µg/kg and 25 µg/kg bw, respectively) at two hours intervals.Animals of group IV received two intraperitoneal injections of cerulein (50 µg/kg and 25 µg/kg bw, respectively) at two hours intervals and the rats received an intraperitoneal injection of 50 mg/kg melatonin 30 min before each cerulein injection.After 12 hours from the last cerulein injection, total cholesterol, triglyceride, LDL, HDL levels was determined.In this study, experimentally induced acute pancreatitis resulted in significantly increase in levels of total cholesterol, triglyceride and LDL (p<0.05), while HDL level significantly decreased compared with control group level (p<0.05). Pretreatment of melatonin to the rats with acute pancreatitis importantly reduced triglyceride and LDL levels compared to pancreatitis group (p<0.05).In conclusion, melatonin pretreatment may alleviate the abnormalities in plasma lipid profilecaused by acute pancreatitis.en_US
dc.identifier.citationKeskin, E., Uluışık, D., (2019). The Protective Effect of Melatonin on Plasma Lipid Profile in Rats with Cerulein-İnduced Acute Pancreatitis. Turkish Journal of Sport and Exercise, 21(2), 332-336. DOI: 10.15314/tsed.541829en_US
dc.identifier.doi10.15314/tsed.541829en_US
dc.identifier.endpage336en_US
dc.identifier.issn2147-5652en_US
dc.identifier.issue2en_US
dc.identifier.startpage332en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/50344
dc.identifier.volume21en_US
dc.institutionauthorKeskin, Ercan
dc.institutionauthorUluışık, Deniz
dc.language.isoenen_US
dc.publisherSelçuk Üniversitesien_US
dc.relation.ispartofTurkish Journal of Sport and Exerciseen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCeruleinen_US
dc.subjectmelatoninen_US
dc.subjectacute pancreatitisen_US
dc.subjectlipid profileen_US
dc.subjectratsen_US
dc.titleThe Protective Effect of Melatonin on Plasma Lipid Profile in Rats with Cerulein-İnduced Acute Pancreatitisen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Spor-24.pdf
Boyut:
689.04 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Dergi Yayın Koleksiyonu
Vet. Fak. Temel Bilimler/Makale Koleksiyonu