Relationship between fetuin-A, inflammation, coronary artery calcification in hemodialysis and peritoneal dialysis patients

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dc.contributor.authorTürkmen K.
dc.contributor.authorKayikçio?lu H.
dc.contributor.authorÖzbek O.
dc.contributor.authorGaipov A.
dc.contributor.authorYerlikaya F.H.
dc.contributor.authorToker A.
dc.contributor.authorTonbul H.Z.
dc.date.accessioned2020-03-26T18:32:58Z
dc.date.available2020-03-26T18:32:58Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractOBJECTIVE: Vascular calcification is commonly seen in patients with end-stage renal disease (ESRD). Fetuin-A has been found to be a vascular calcification inhibitor and its level is significantly low in ESRD patients. The aim of our study was to investigate the relation between coronary artery calcification, inflammation and fetuin-A levels in peritoneal dialysis (PD) and hemodialysis (HD) patients. MATERIAL and METHODS: 46 PD (M/F=28/18) and 34 (M/F=20/14) HD patients were included in the study. Coronary artery calcification scoring was made by multi slice computed tomography. PD and HD patients were divided into 2 groups according to their median CACS values Serum levels of fetuin-A, CRP, IL-6 and TNF-a are studied. RESULTS: There were no differences in demographic features of PD and HD patients. There was a correlation between CACS, advanced age, dialysis vintage and fetuin-A. We could not find any correlation between infiammatory markers and CACS. There was a statistically significant difference between fetuin-A and CACS groups. CONCLUSION: Age, duration of dialysis, fetuin-A levels were found to be related to CACS in PD and HD patients. Fetuin-A may play a role in increased mortality in this population via facilitating CACS.en_US
dc.identifier.doi10.5262/tndt.2012.1002.02en_US
dc.identifier.endpage117en_US
dc.identifier.issn1300-7718en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage111en_US
dc.identifier.urihttps://dx.doi.org/10.5262/tndt.2012.1002.02
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28810
dc.identifier.volume21en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Nephrology, Dialysis and Transplantation Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectFetuin-Aen_US
dc.subjectHemodialysisen_US
dc.subjectInflammationen_US
dc.subjectPeritoneal dialysisen_US
dc.subjectVascular calcificationen_US
dc.titleRelationship between fetuin-A, inflammation, coronary artery calcification in hemodialysis and peritoneal dialysis patientsen_US
dc.typeArticleen_US

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