Structures, Functions and Expressions of GnRH and GnRH Receptor in Peripheral Reproductive Organs and Their Regulation by Estradiol-17 beta
Küçük Resim Yok
Tarih
2015
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ISLAMIC AZAD UNIV, RASHT
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Studies have shown that estradiol-17 beta (E-2) regulates gonadotropin-releasing hormone (GnRH) and GnRH receptor expression in hypothalamus and pituitary. Several studies have shown that GnRH and its receptor are also expressed in peripheral reproductive organs and little is known about their regulations. In this study, GnRH and GnRH receptor structures, functions, their peripheral expressions and regulations by E-2 were reviewed. Several in vivo and in vitro conducted studies indicate that E-2 decreases the expression of GnRH mRNA and regulates GnRH receptor expression in a time dependent manner. Nevertheless, the exact mechanism has not been clearly explained yet.
Açıklama
Anahtar Kelimeler
estradiol, GnRH, ovary, oviduct, uterus
Kaynak
IRANIAN JOURNAL OF APPLIED ANIMAL SCIENCE
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
5
Sayı
4
